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Journal ArticleDOI

Principles of Neural Science

Michael P. Alexander
- 06 Jun 1986 - 
- Vol. 255, Iss: 21, pp 3021-3021
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TLDR
The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.
Abstract
I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

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References
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Rapid eye movement sleep parasomnias.

TL;DR: The recognition of RBD has shed additional scientific light on the "bumps in the night"; expanded knowledge of states of being and state dissociation; opened up new areas of research on brain and mind dysfunction during sleep; and reaffirmed the vital link between basic research and clinical medicine.
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A Test for Geoengineering

TL;DR: It is argued that geoengineering cannot be tested without full-scale implementation, and weather and climate variability preclude observation of the climate response without a large, decade-long forcing.
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The Role of Dopamine Receptors in Regulating the Size of Axonal Arbors

TL;DR: The results suggest that individual dopaminergic axons in D2(−/−) mice have reached maximal arbor size, and the D2 receptor may play a role in modulating the extent of the terminal arbor of SNpc neurons.
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Increases in strychnine-insensitive glycine binding sites in cerebral cortex of chronic schizophrenics: evidence for glutamate hypothesis.

TL;DR: The results suggest that the increases in NMDA-associated glycine binding sites, possibly ascribed to the postsynaptic compensation for impaired glutamatergic neurotransmission, might be implicated in the pathophysiology of schizophrenia.
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Apolipoprotein D takes center stage in the stress response of the aging and degenerative brain

TL;DR: Apolipoprotein D emerges as an evolutionarily conserved anti-stress protein that is induced by oxidative stress and inflammation and may prove to be an effective therapeutic agent against a variety of neuropathologies, and even against aging.
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