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Journal ArticleDOI

Principles of Neural Science

Michael P. Alexander
- 06 Jun 1986 - 
- Vol. 255, Iss: 21, pp 3021-3021
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TLDR
The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.
Abstract
I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

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References
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Journal ArticleDOI

Hierarchical organization unveiled by functional connectivity in complex brain networks.

TL;DR: This work study synchronization dynamics in the cortical brain network of the cat finds that in the biologically plausible regime the dynamics exhibits a hierarchical modular organization, in particular, revealing functional clusters coinciding with the anatomical communities at different scales.
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Emotion Enhances Learning via Norepinephrine Regulation of AMPA-Receptor Trafficking

TL;DR: Examination of the role of NE in contextual memory formation and in the synaptic delivery of GluR1-containing alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (AMPA)-type glutamate receptors during long-term potentiation (LTP), a candidate synaptic mechanism for learning, indicates that NE-driven phosphorylation of GLUR1 facilitates the synaptic deliveries of Glamorganically-containing AMPARs.
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Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs

TL;DR: The present findings may have implications for pathogenesis: because NSAIDs block the calcium-dependent postsynaptic cascade that induces excitotoxic cell death in NMDA-reactive neurons, and because histamine potentiates such events, exciteotoxicity may deserve additional investigation in AD.
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Isotropic Fractionator: A Simple, Rapid Method for the Quantification of Total Cell and Neuron Numbers in the Brain

TL;DR: A novel, fast, and inexpensive method to quantify total numbers of neuronal and non-neuronal cells in the brain or any dissectable regions thereof, which consists of transforming highly anisotropic brain structures into homogeneous, isotropic suspensions of cell nuclei, which can be counted and identified immunocytochemically as neuronal or non-NEuronal.
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Adult attachment and the suppression of unwanted thoughts.

TL;DR: These experiments indicate that dismissing-avoidant adults are capable of suppressing the latent activation of their attachment system and are not simply concealing latent distress.
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