Journal ArticleDOI
Principles of Neural Science
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The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.Abstract:
I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his orread more
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References
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Journal ArticleDOI
Trust and Credit: The Role of Appearance in Peer-to-peer Lending
TL;DR: This article found that borrowers who appear more trustworthy have higher probabilities of having their loans funded and default less often, while borrowers who appeared more trustworthy had better credit scores and defaulted less often.
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Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation
Christopher G. Vecsey,Joshua D. Hawk,K. Matthew Lattal,Joel M. Stein,Sara A. Fabian,Michelle A. Attner,Sara M. Cabrera,Conor B. McDonough,Paul K. Brindle,Ted Abel,Marcelo A. Wood +10 more
TL;DR: It is shown that the enhancement of hippocampus-dependent memory and hippocampal synaptic plasticity by HDAC inhibitors is mediated by the transcription factor cAMP response element-bindingprotein (CREB) and the recruitment of the transcriptional coactivator and histone acetyltransferase CREB-binding protein (CBP) via the CREB -binding domain of CBP.
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Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier.
TL;DR: Any novel antioxidant molecules designed as potential neuroprotective treatment in acute or chronic neurological disorders should have the mandatory prerequisite that they can cross the blood brain barrier after systemic administration.
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ThermoTRP channels and beyond: mechanisms of temperature sensation
TL;DR: The thermoTRPs, a subset of transient receptor potential ion channels are activated by distinct physiological temperatures, and are involved in converting thermal information into chemical and electrical signals within the sensory nervous system.
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Compositional pattern producing networks: A novel abstraction of development
TL;DR: Results produced with CPPNs through interactive evolution of two-dimensional images show that such an encoding can nevertheless produce structural motifs often attributed to more conventional developmental abstractions, suggesting that local interaction may not be essential to the desirable properties of natural encoding in the way that is usually assumed.