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Journal ArticleDOI

Principles of Neural Science

Michael P. Alexander
- 06 Jun 1986 - 
- Vol. 255, Iss: 21, pp 3021-3021
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TLDR
The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.
Abstract
I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

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Citations
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Journal ArticleDOI

KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development

TL;DR: Evidence that Syne-2/Nesprin-2 forms complexes with either SUN1 or SUN2 at the nuclear envelope to connect the nucleus with dynein/dynactin and kinesin molecular motors during the nuclear migrations in the retina will advance the understanding of the mechanism of nuclear migration in the mammalian retina.
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Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration.

TL;DR: At least two different pathways promote net sterol excretion from the CNS and one probably involves the movement of cholesterol or one of its metabolites across the blood-brain barrier and may more closely mirror sterol turnover in pools such as glial cell membranes and myelin.
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Brain Activation of Children With Developmental Coordination Disorder is Different Than Peers

TL;DR: The results suggest that the group with DCD relied on visuospatial processing to complete the task, and demonstrates differences in neural networks and patterns of brain activation relative to same-age peers.
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Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy

TL;DR: The results support the interpretation of the increase of the cortical diffusion coefficient during finger opposition being due to the functional increase in cortical blood flow rate related to vasodilation.
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Three-dimensional migration of neurites is mediated by adhesion site density and affinity

TL;DR: Two- and three-dimensional neurite outgrowth demonstrated a bi-phasic dependence on RGD concentration for both the linear and cyclic peptide, with intermediate adhesion site densities yielding maximal neurite extension and higher densities inhibiting outgrowth.
References
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Book

Machine Learning : A Probabilistic Perspective

TL;DR: This textbook offers a comprehensive and self-contained introduction to the field of machine learning, based on a unified, probabilistic approach, and is suitable for upper-level undergraduates with an introductory-level college math background and beginning graduate students.
Journal ArticleDOI

Brain-computer interfaces for communication and control.

TL;DR: With adequate recognition and effective engagement of all issues, BCI systems could eventually provide an important new communication and control option for those with motor disabilities and might also give those without disabilities a supplementary control channel or a control channel useful in special circumstances.
Journal ArticleDOI

Structure and function of the blood–brain barrier

TL;DR: The structure and function of the BBB is summarised, the physical barrier formed by the endothelial tight junctions, and the transport barrier resulting from membrane transporters and vesicular mechanisms are described.
Book

Being There: Putting Brain, Body, and World Together Again

TL;DR: Clark as mentioned in this paper argues that the mental has been treated as a realm that is distinct from the body and the world, and argues that a key to understanding brains is to see them as controllers of embodied activity.
Journal ArticleDOI

Nature-nuture reconceptualized in developmental perspective: A bioecological model.

TL;DR: The authors propose an empirically testable theoretical model that goes beyond and qualifies the established behavioral genetics paradigm by allowing for nonadditive synergistic effects, direct measures of the environment, and mechanisms of organism-environment interaction through which genotypes are transformed into phenotypes.
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