Tumor and its microenvironment: A synergistic interplay
Veronica Catalano,Alice Turdo,Simone Di Franco,Francesco Dieli,Matilde Todaro,Giorgio Stassi +5 more
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TLDR
The synergistic effect of hypoxia inducible factors (HIFs) and vascular endothelial growth factors (VEGFs) in the successful outgrowth of metastasis is focused on, integrating therefore many of the emerging models and theories in the field.About:
This article is published in Seminars in Cancer Biology.The article was published on 2013-12-01 and is currently open access. It has received 343 citations till now. The article focuses on the topics: Tumor microenvironment & Tumor progression.read more
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Interplay between Tumor Microenvironment and Cancer Cells.
TL;DR: This issue contains interesting articles, which were accepted after a rigorous peer review process, and will advance researchers and readers knowledge on various aspects of tumor cell-microenvironment interactions and will provide insight into new research focused on this area and potential therapeutic interventions.
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A synergistic chemodynamic-photodynamic-photothermal therapy platform based on biodegradable Ce-doped MoOx nanoparticles.
TL;DR: A one-step hydrothermal synthesis for Ce-doped MoOx (CMO) nanomaterials is reported, which shows high absorption in the NIR II regime and a high photothermal conversion efficiency, which makes CMO nanocatalysts ideal biodegradable nanotheranostic agents for synergistic chemodynamic-photodynamic-Photothermal antitumor therapy.
Posted Content
Niche inheritance: a cooperative pathway to enhance cancer cell fitness though ecosystem engineering
Kimberline R. Yang,Steven M. Mooney,Jelani C. Zarif,Donald S. Coffey,Russell S. Taichman,Kenneth J. Pienta +5 more
TL;DR: Ecological dispersion theory can be utilized to describe and model the steps and barriers involved in a successful diaspora as the cancer cells leave the original host organ and migrate to new host organs to successfully establish a new metastatic community.
References
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Global cancer statistics
TL;DR: A substantial proportion of the worldwide burden of cancer could be prevented through the application of existing cancer control knowledge and by implementing programs for tobacco control, vaccination, and early detection and treatment, as well as public health campaigns promoting physical activity and a healthier dietary intake.
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A genetic model for colorectal tumorigenesis
Eric R. Fearon,Bert Vogelstein +1 more
TL;DR: A model for the genetic basis of colorectal neoplasia that includes the following salient features is presented, which may be applicable to other common epithelial neoplasms, in which tumors of varying stage are more difficult to study.
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Tumor Angiogenesis: Therapeutic Implications
TL;DR: This new capillary growth is even more vigorous and continuous than a similar outgrowth of capillary sprouts observed in 2016 and is likely to be accompanied by neovascularization.
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Immunity, Inflammation, and Cancer
TL;DR: The principal mechanisms that govern the effects of inflammation and immunity on tumor development are outlined and attractive new targets for cancer therapy and prevention are discussed.
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Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery,Jean Paul Thiery,Hervé Acloque,Ruby Yun-Ju Huang,Ruby Yun-Ju Huang,M. Angela Nieto +5 more
TL;DR: The mesenchymal state is associated with the capacity of cells to migrate to distant organs and maintain stemness, allowing their subsequent differentiation into multiple cell types during development and the initiation of metastasis.