Open Access
Two-Dose Intrapartum/Newborn Nevirapine and Standard Antiretroviral Therapy to Reduce Perinatal HIV Transmission
Alejandro Dorenbaum,Coleen K. Cunningham,Richard D. Gelber,Mary Culnane,Lynne M. Mofenson,Paula Britto,Marie-Louise Newell,Jean François Delfraissy,Bethann Cunningham-Schrader,John L. Sullivan +9 more
TLDR
Risk of perinatal HIV transmission was low and no benefit from additional intrapartum/newborn nevirapine was demonstrated when women received prenatal care and antenatal ART, and elective cesarean section was made available.About:
The article was published on 2017-01-01 and is currently open access. It has received 368 citations till now. The article focuses on the topics: Nevirapine.read more
Citations
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Book ChapterDOI
128 – Human Immunodeficiency Virus Infection in Women
Susan E. Cohn,Rebecca A. Clark +1 more
Journal ArticleDOI
The time to recommend antenatal HIV screening for all pregnant women has arrived.
John B. Ziegler,Nicholas Graves +1 more
TL;DR: The facts show that existing practice in Australia fails to identify a number of preventable cases of mother-to-child transmission, and any recommendation to offer testing to all pregnant women would need to be accompanied by systematic strengthening of counselling and consent procedures.
Journal ArticleDOI
Treatment of acute C hepatitis in HIV-infected patients.
Sabrina Audagnotto,Francesco Giuseppe De Rosa,Olivia Bargiacchi,Silvia Garazzino,L. Veronese,Giuseppe Cariti,Giovanni Di Perri +6 more
TL;DR: PegIFN a-2b was administered on a openlabel basis to 4 consecutive HIV-infected patients who developed ACH with rates of SVR higher than those achievable with pegIFN and ribavirin in chronic C hepatitis, with the primary endpoint the SVR, defined as a negative RT-PCR result 24 weeks after the end of treatment.
Dissertation
The role of HIV- and SIV-specific CD8+ T cells in the establishment of persistent HIV and SIV infections.
TL;DR: This dissertation aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the response of the immune system to EMTs.
Dissertation
Adherence and sustained access to antiretroviral treatment in the Free State public health sector: a gender perspective
De Reuck,Chantell Jacqualine +1 more
TL;DR: Examining how gender influences adherence to ARV medications and sustained access to treatment among patients on ART in the Free State public health sector found that the strongest predictors of medication nonadherence among men included financial difficulties in visiting hospital facilities and poor treatment knowledge.
References
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Journal ArticleDOI
Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial
Laura Guay,Philippa Musoke,Thomas Fleming,Danstan Bagenda,Melissa Allen,Clemensia Nakabiito,Joseph Sherman,Paul M Bakaki,Constance Ducar,Martina Deseyve,Lynda Emel,Mark Mirochnick,Mary Glenn Fowler,Lynne M. Mofenson,Paolo G. Miotti,Kevin Dransfield,Dorothy Bray,Francis Mmiro,J. Brooks Jackson +18 more
TL;DR: Nevirapine lowered the risk of HIV-1 transmission during the first 14-16 weeks of life by nearly 50% in a breastfeeding population, suggesting this simple and inexpensive regimen could decrease mother-to-child HIV- 1 transmission in less-developed countries.
Journal ArticleDOI
Treatment for adult HIV infection : 2006 recommendations of the international AIDS society-USA panel
Scott M. Hammer,Michael S. Saag,Mauro Schechter,Julio S. G. Montaner,Robert T. Schooley,Donna M. Jacobsen,Melanie A. Thompson,Charles C. J. Carpenter,Margaret A. Fischl,Brian Gazzard,Jose M. Gatell,Martin S. Hirsch,David Katzenstein +12 more
TL;DR: The virologic target for patients with treatment failure is now a plasma HIV-1 RNA level below 50 copies/mL, making delivery of state-of-the-art care challenging.
Journal ArticleDOI
Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012).
Susan H. Eshleman,Martin Mracna,Laura Guay,Martina Deseyve,Shawn Cunningham,Mark Mirochnick,Philippa Musoke,Thomas Fleming,Mary Glenn Fowler,Lynne M. Mofenson,Francis Mmiro,J. Brooks Jackson +11 more
TL;DR: NVPR was detected more frequently in infants than women following NVP prophylaxis, and different patterns of NVPR mutations were detected in women versus infants, and NVP-resistant HIV-1 faded from detection in women and infants over time.
Journal ArticleDOI
Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1
Laurent Mandelbrot,Aline Landreau-Mascaro,Claire Rekacewicz,Alain Berrebi,Jean Louis Bénifla,Marianne Burgard,Eric Lachassine,Béatrice Barret,Marie-Laure Chaix,André Bongain,Nicole Ciraru-Vigneron,Catherine Crenn-Hebert,Jean-François Delfraissy,Christine Rouzioux,Marie-Jeanne Mayaux,Stéphane Blanche +15 more
TL;DR: Lamivudine-zidovudine prophylaxis therapy may be effective in preventing maternal-infant HIV transmission, however, severe adverse effects and emergence of resistance to lamivUDine occurred.
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