Open Access
Two-Dose Intrapartum/Newborn Nevirapine and Standard Antiretroviral Therapy to Reduce Perinatal HIV Transmission
Alejandro Dorenbaum,Coleen K. Cunningham,Richard D. Gelber,Mary Culnane,Lynne M. Mofenson,Paula Britto,Marie-Louise Newell,Jean François Delfraissy,Bethann Cunningham-Schrader,John L. Sullivan +9 more
TLDR
Risk of perinatal HIV transmission was low and no benefit from additional intrapartum/newborn nevirapine was demonstrated when women received prenatal care and antenatal ART, and elective cesarean section was made available.About:
The article was published on 2017-01-01 and is currently open access. It has received 368 citations till now. The article focuses on the topics: Nevirapine.read more
Citations
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Journal ArticleDOI
Contraception use, family planning, and unprotected sex: few differences among HIV-infected and uninfected postpartum women in four US states.
Tracey E. Wilson,Linda J. Koenig,Jeannette R. Ickovics,Emmanuel B. Walter,Amy Suss,Maria I Fernandez,Perinatal Guidelines Evaluation +6 more
TL;DR: In this paper, the authors describe pregnancy intentions and contraceptive use among a postpartum sample of women with and at risk for HIV infection, recruited from prenatal clinics in 4 US states between June 1996-November 1998.
Journal ArticleDOI
Implementing anti-retroviral triple therapy to prevent HIV mother-to-child transmission: a public health approach in resource-limited settings.
Cristina Marazzi,P Germano,Giuseppe Liotta,Giovanni Guidotti,Sandra Loureiro,Aurelio Gomes,Maria C. Valls Blazquez,Pasquale Narciso,Carlo Federico Perno,Sandro Mancinelli,Annamaria Doro Altan,Karin Nielsen-Saines,Leonardo Palombi +12 more
TL;DR: A retrospective cohort study of HIV-infected pregnant women and their infants enrolled in the DREAM programme for prevention of HIV mother-to-child transmission (MTCT) in Mozambique finds that approximately 80% of pregnant women completed the treatment protocol.
Journal ArticleDOI
Risk of congenital cytomegalovirus infection among HIV-exposed uninfected infants is not decreased by maternal nelfinavir use during pregnancy
Soren Gantt,Soren Gantt,Erin Leister,Denise L. Jacobsen,I. Boucoiran,Meei Li Huang,Meei Li Huang,Keith R. Jerome,Keith R. Jerome,Gonzague Jourdain,Nicole Ngo-Giang-Huong,Sandra K. Burchett,Lisa M. Frenkel,Lisa M. Frenkel +13 more
TL;DR: Among HIV‐exposed uninfected infants, c CMV infection was associated with adverse perinatal outcomes and NFV use in pregnancy was not associated with protection against cCMV.
Journal ArticleDOI
Reducción de la transmisión madre hijo del VIH en Colombia: dos años de experiencia nacional, 2003-2005
TL;DR: La reduccion of the transmision madre hijo de VIH es una intervencion preventiva eficaz that favorece el fortalecimiento of los servicios de control prenatal and mayor captacion tardia en el embarazo.
Journal ArticleDOI
Current guidelines on management of HIV-infected pregnant women: impact on mode of delivery.
TL;DR: Recommending vaginal delivery among HIV-infected women in selected cases was well accepted, particularly once the policy became established, Nevertheless, a high proportion of HIV- Infected women will continue to require caesarean section delivery.
References
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Journal ArticleDOI
Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial
Laura Guay,Philippa Musoke,Thomas Fleming,Danstan Bagenda,Melissa Allen,Clemensia Nakabiito,Joseph Sherman,Paul M Bakaki,Constance Ducar,Martina Deseyve,Lynda Emel,Mark Mirochnick,Mary Glenn Fowler,Lynne M. Mofenson,Paolo G. Miotti,Kevin Dransfield,Dorothy Bray,Francis Mmiro,J. Brooks Jackson +18 more
TL;DR: Nevirapine lowered the risk of HIV-1 transmission during the first 14-16 weeks of life by nearly 50% in a breastfeeding population, suggesting this simple and inexpensive regimen could decrease mother-to-child HIV- 1 transmission in less-developed countries.
Journal ArticleDOI
Treatment for adult HIV infection : 2006 recommendations of the international AIDS society-USA panel
Scott M. Hammer,Michael S. Saag,Mauro Schechter,Julio S. G. Montaner,Robert T. Schooley,Donna M. Jacobsen,Melanie A. Thompson,Charles C. J. Carpenter,Margaret A. Fischl,Brian Gazzard,Jose M. Gatell,Martin S. Hirsch,David Katzenstein +12 more
TL;DR: The virologic target for patients with treatment failure is now a plasma HIV-1 RNA level below 50 copies/mL, making delivery of state-of-the-art care challenging.
Journal ArticleDOI
Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012).
Susan H. Eshleman,Martin Mracna,Laura Guay,Martina Deseyve,Shawn Cunningham,Mark Mirochnick,Philippa Musoke,Thomas Fleming,Mary Glenn Fowler,Lynne M. Mofenson,Francis Mmiro,J. Brooks Jackson +11 more
TL;DR: NVPR was detected more frequently in infants than women following NVP prophylaxis, and different patterns of NVPR mutations were detected in women versus infants, and NVP-resistant HIV-1 faded from detection in women and infants over time.
Journal ArticleDOI
Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1
Laurent Mandelbrot,Aline Landreau-Mascaro,Claire Rekacewicz,Alain Berrebi,Jean Louis Bénifla,Marianne Burgard,Eric Lachassine,Béatrice Barret,Marie-Laure Chaix,André Bongain,Nicole Ciraru-Vigneron,Catherine Crenn-Hebert,Jean-François Delfraissy,Christine Rouzioux,Marie-Jeanne Mayaux,Stéphane Blanche +15 more
TL;DR: Lamivudine-zidovudine prophylaxis therapy may be effective in preventing maternal-infant HIV transmission, however, severe adverse effects and emergence of resistance to lamivUDine occurred.
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