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Journal ArticleDOI

Use of comparative transcriptome analysis to identify candidate genes related to albinism in channel catfish (Ictalurus punctatus)

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TLDR
A possible mechanism for the mutation of the catfish Hps4 gene, which affects regulation of expression of genes in the tyrosine metabolism pathway, is identified and provided a theoretical basis for further understanding of the pathogenesis of albinism in catfish.
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This article is published in Aquaculture.The article was published on 2019-02-01. It has received 12 citations till now. The article focuses on the topics: Catfish & Melanosome transport.

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A germline mutation in BLOC1S3/reduced pigmentation causes a novel variant of Hermansky Pudlak syndrome (HPS8)

TL;DR: In this paper, a homozygous germline frameshift mutation in BLOC1S3 (p.Gln150ArgfsX75) was identified in all affected individuals.
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Combined use of single molecule real-time DNA sequencing technology and culture-dependent methods to analyze the functional microorganisms in inoculated raw wheat Qu.

TL;DR: Inoculated raw wheat Qu (IRWQ), which can be produced with high efficiency and low cost while maintaining stable quality, is a new Qu that has been applied to Huangjiu brewing and molds were the main contributors of glucoamylase, amylase and protease activities.
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New insights into the impacts of huangjiu compontents on intoxication.

TL;DR: Wang et al. as mentioned in this paper used the Cryprinus carpio intoxication model to compare the differences in intoxication effect of alcoholic beverages and assess the impacts of huangjiu components on intoxication for the first time.
References
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Journal ArticleDOI

Trimmomatic: a flexible trimmer for Illumina sequence data

TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

TL;DR: Bowtie extends previous Burrows-Wheeler techniques with a novel quality-aware backtracking algorithm that permits mismatches and can be used simultaneously to achieve even greater alignment speeds.
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Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

TL;DR: The results suggest that Cufflinks can illuminate the substantial regulatory flexibility and complexity in even this well-studied model of muscle development and that it can improve transcriptome-based genome annotation.
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TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

TL;DR: TopHat2 is described, which incorporates many significant enhancements to TopHat, and combines the ability to identify novel splice sites with direct mapping to known transcripts, producing sensitive and accurate alignments, even for highly repetitive genomes or in the presence of pseudogenes.
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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

TL;DR: It is shown that phosphorylation and activation of the 5′-AMP-activated protein kinase (AMPK) are stimulated with globular and full-length Ad in skeletal muscle and only with full- lengths Ad in the liver, indicating that stimulation of glucose utilization and fatty-acid oxidation by Ad occurs through activation of AMPK.
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