C
Charles E. Rupprecht
Researcher at Wistar Institute
Publications - 484
Citations - 29552
Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.
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Journal ArticleDOI
New world bats harbor diverse influenza A viruses.
Suxiang Tong,Xueyong Zhu,Yan Li,Mang Shi,Jing Zhang,Melissa Bourgeois,Hua Yang,Xianfeng Chen,Sergio Recuenco,Jorge Gomez,Li-Mei Chen,Adam Johnson,Ying Tao,C. Dreyfus,Wenli Yu,Ryan McBride,Paul J. Carney,Amy T. Gilbert,Jessie Chang,Zhu Guo,Charles T. Davis,James C. Paulson,James Stevens,Charles E. Rupprecht,Charles E. Rupprecht,Edward C. Holmes,Edward C. Holmes,Ian A. Wilson,Ruben O. Donis +28 more
TL;DR: Using consensus degenerate RT-PCR, a novel influenza A virus is identified in a flat-faced fruit bat from Peru, indicating that bats constitute a potentially important and likely ancient reservoir for a diverse pool of influenza viruses.
Journal ArticleDOI
Estimating the global burden of endemic canine rabies.
Katie Hampson,Laurent Coudeville,Tiziana Lembo,Maganga Sambo,Alexia Kieffer,Michaël Attlan,Jacques Barrat,Jesse D. Blanton,Deborah J. Briggs,Sarah Cleaveland,Peter Costa,Conrad M. Freuling,Elly Hiby,Lea Knopf,Fernando Leanes,François-Xavier Meslin,A. E. Metlin,Mary Elizabeth Miranda,Thomas Müller,Louis Hendrik Nel,Sergio Recuenco,Charles E. Rupprecht,Charles E. Rupprecht,Carolin L. Schumacher,Louise H. Taylor,Marco Antonio Natal Vigilato,Jakob Zinsstag,Jonathan Dushoff +27 more
TL;DR: Investment in dog vaccination, the single most effective way of reducing the disease burden, has been inadequate and that the availability and affordability of PEP needs improving, demonstrating that collaboration by medical and veterinary sectors could dramatically reduce the current large, and unnecessary, burden of rabies on affected communities.
Journal ArticleDOI
A distinct lineage of influenza A virus from bats
Suxiang Tong,Yan Li,Pierre Rivailler,Christina Conrardy,Danilo A. Alvarez Castillo,Li-Mei Chen,Sergio Recuenco,James A. Ellison,Charles T. Davis,Ian A. York,Amy S. Turmelle,David Moran,Shannon Rogers,Mang Shi,Ying Tao,Michael R. Weil,Kevin Tang,Lori A. Rowe,Scott Sammons,Xiyan Xu,Michael Frace,Kim A. Lindblade,Nancy J. Cox,Larry J. Anderson,Charles E. Rupprecht,Ruben O. Donis +25 more
TL;DR: Despite its divergence from known influenza A virus, the bat virus is compatible for genetic exchange with human influenza viruses in human cells, suggesting the potential capability for reassortment and contributions to new pandemic or panzootic influenza A viruses.
Journal ArticleDOI
Case Definitions, Diagnostic Algorithms, and Priorities in Encephalitis: Consensus Statement of the International Encephalitis Consortium
Arun Venkatesan,Allan R. Tunkel,Karen C. Bloch,Adam S. Lauring,James J. Sejvar,Ari Bitnun,Jean-Paul Stahl,Alexandra Mailles,M. Drebot,Charles E. Rupprecht,Jonathan S. Yoder,Jennifer R. Cope,Michael R. Wilson,Richard J. Whitley,John S. Sullivan,Julia Granerod,Cheryl A Jones,Keith Eastwood,Katherine N. Ward,Katherine N. Ward,David N Durrheim,M. V. Solbrig,L. Guo-Dong,Carol A. Glaser,Heather Sheriff,David W. Brown,Eileen C. Farnon,Sharon Messenger,Beverley J. Paterson,Ariane Soldatos,Sharon L. Roy,Govinda S. Visvesvara,Michael L. Beach,Roger S. Nasci,Carol Pertowski,Scott Schmid,Lisa Rascoe,Joel M. Montgomery,Suxiang Tong,Robert F. Breiman,Richard Franka,Matt Keuhnert,Fred Angulo,James D. Cherry +43 more
TL;DR: A consensus document is presented that proposes a standardized case definition and diagnostic guidelines for evaluation of adults and children with suspected encephalitis and will serve as a practical aid to clinicians evaluating patients with suspectedEncephalitis.
Journal ArticleDOI
A comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special?
Angela D. Luis,Angela D. Luis,David T. S. Hayman,Thomas J. O'Shea,Paul M. Cryan,Amy T. Gilbert,Juliet R. C. Pulliam,Juliet R. C. Pulliam,James N. Mills,Mary E. Timonin,Craig K. R. Willis,Andrew A. Cunningham,Anthony R. Fooks,Charles E. Rupprecht,James L. N. Wood,Colleen T. Webb +15 more
TL;DR: The results point to a new hypothesis to explain in part why bats host more zoonotic viruses per species: the stronger effect of sympatry in bats and more viruses shared between bat species suggests that interspecific transmission is more prevalent among bats than among rodents.