E
Edward G. Lakatta
Researcher at National Institutes of Health
Publications - 902
Citations - 95504
Edward G. Lakatta is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Blood pressure & Population. The author has an hindex of 146, co-authored 858 publications receiving 88637 citations. Previous affiliations of Edward G. Lakatta include University of Pittsburgh & University College London.
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Effect of age on the components of atrioventricular conduction in normal man
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Reprogramming paces the heart
TL;DR: Rodent cardiomyocytes are converted into pacemaker cells by viral delivery of a single transcription-factor gene.
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Mouse RAGE variant 4 is a dominant membrane receptor that does not shed to generate soluble RAGE
TL;DR: In this article, the authors characterized mRAGEV4 isoreceptor in comparison with the full-length m-RAGE (mRAGEFL) and showed that the two isoforms display very different cellular behaviors.
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Predictive value of pulse wave velocity for cardiovascular events in 15220 subjects: an individual participant meta-analysis on behalf of the pwv collaborative group: ht.3.03
Yoav Ben-Shlomo,C.M. McEniery,Pierre Boutouyrie,James D. Cameron,C.-H. Chen,Kennedy Cruickshank,Edward G. Lakatta,S. Laurent,João Maldonado,Anne B. Newman,Mitsuru Ohishi,Bruno Pannier,Telmo Pereira,Tomoki Shokawa,Kim Sutton-Tyrell,David J. Webb,I.B. Wilkinson,T Willum Hansen,Sophia Zoungas,John R. Cockcroft +19 more
Cycling Proteins Generates Robust Rhythmic Local Ca 2+ Releases in Cardiac Pacemaker Cells
Syevda Tagirova Sirenko,Dongmei Yang,Yue Li,Alexey E. Lyashkov,Yevgeniya O. Lukyanenko,Edward G. Lakatta,Tatiana M. Vinogradova +6 more
TL;DR: The ability of sinoatrial node cells to generate larger and rhythmic local Ca releases was associated with increased abundance of sarcoplasmic reticulum Ca-ATPase, reduced abundance of the SERCA inhibitor phospholamban, and increased Ca-dependent phosphorylation of phosphol amban and RyR.