E
Edward G. Lakatta
Researcher at National Institutes of Health
Publications - 902
Citations - 95504
Edward G. Lakatta is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Blood pressure & Population. The author has an hindex of 146, co-authored 858 publications receiving 88637 citations. Previous affiliations of Edward G. Lakatta include University of Pittsburgh & University College London.
Papers
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Journal ArticleDOI
Compatibility of superparamagnetic iron oxide nanoparticle labeling for 1H MRI cell tracking with 31P MRS for bioenergetic measurements
Zhuoli Zhang,Brynne Hancock,Stephanie Leen,Sharan Ramaswamy,Steven J. Sollott,Kenneth R. Boheler,Magdalena Juhaszova,Edward G. Lakatta,Richard G. Spencer,Kenneth W. Fishbein +9 more
TL;DR: 31P NMR spectra can be obtained from cells labeled with sufficient iron to permit visualization by 1H imaging protocols and that these spectra have sufficient quality to be used to assess metabolic status, and introduces the possibility of using localized 31P MRS to evaluate the viability of iron‐labeled therapeutic cells as well as surrounding host tissue in vivo.
Journal ArticleDOI
β-Adrenergic Stimulation Synchronizes a Broad Spectrum of Action Potential Firing Rates of Cardiac Pacemaker Cells toward a Higher Population Average.
TL;DR: In this paper, the authors measured the β-adrenergic receptors (βAR) responses among 166 single sinoatrial node (SAN) cells isolated from 33 guinea pig hearts.
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Ongoing Dual-Angle Measurements for the Correction of Partial Saturation in 31P MR Spectroscopy
Damian J. Tyler,Orlando Lopez,Mark A. Cole,Carolyn A. Carr,Daniel J. Stuckey,Edward G. Lakatta,Kieran Clarke,Richard G. Spencer +7 more
TL;DR: Using 31P magnetic resonance spectroscopy of the perfused rat heart undergoing ischemia‐reperfusion, it is demonstrated that signal alternations in the data acquired by the dual‐angle approach are eliminated by the ongoingDual‐angle T1 measurement correction scheme, meaning that metabolite concentration and T1 measurements can be made throughout the course of the ischemIA‐rePerfusion protocol.
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Sex Differences in Longitudinal Determinants of Carotid Intima Medial Thickening With Aging in a Community-Dwelling Population: The Baltimore Longitudinal Study on Aging.
Ajoy C. Karikkineth,Majd AlGhatrif,Majd AlGhatrif,Matt T. Oberdier,Christopher H. Morrell,Elango Palchamy,James B. Strait,Luigi Ferrucci,Edward G. Lakatta +8 more
TL;DR: Age‐associated changes in IMT were modulated by concurrent changes of low‐density lipoprotein in both sexes, and of pulsatile and mean blood pressure in women but not men.