E
Edward G. Lakatta
Researcher at National Institutes of Health
Publications - 902
Citations - 95504
Edward G. Lakatta is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Blood pressure & Population. The author has an hindex of 146, co-authored 858 publications receiving 88637 citations. Previous affiliations of Edward G. Lakatta include University of Pittsburgh & University College London.
Papers
More filters
Journal Article
Abstract 15658: Arginine-vasopressin Levels Are Increased in Heart Failure With Preserved Ejection Fraction and Correlate With LV Hypertrophy
Julio A. Chirinos,Amer Ahmed Syed,Haideliza Soto-Calderon,Izzah Vassim,Swapna Varakantam,Maheswara R Koppula,Scott Akers,Alexei Y. Bagrov,Wen Wei,Edward G. Lakatta,Olga V. Fedorova +10 more
TL;DR: Arginine-Vasopressin exerts a variety of effects, in addition to its antidiuretic effect via V2 receptors in the kidneys, AVP has vasoconstrictive effects via its action on V1a receptor in the peripheral vasculature.
Journal Article
Abstract 1967: Genome-wide Association Analysis of 25,330 Individuals Identifies Multiple Loci Associated With Resting Heart Rate
Mark Eijgelsheim,Christpher Newton-Cheh,Nona Sotoodehnia,Paul I.W. de Bakker,Martina Müller,Alanna C. Morrison,Albert V. Smith,Aaron Isaacs,Serena Sanna,Marcus Dörr,Pau Navarro,Christian Fuchsberger,James F. Wilson,Peter P. Pramstaller,Cornelia M. van Duijn,Edward G. Lakatta,Stephan B. Felix,Vilmundur Gudnason,Arne Pfeufer,Susan R. Heckbert,Bruno H. Stricker,Eric Boerwinkle,Christopher J. O'Donnell +22 more
Journal ArticleDOI
Commentaries on viewpoint: The cardiac contraction cycle: is Ca2+ going local? Counterpoint.
Hannes Reuter,William E. Louch,Fabien Brette,James S.K. Sham,Hui Sun,Xiao-Ru Yang,Christian Soeller,Edward G. Lakatta,Ravi C. Balijepalli +8 more
TL;DR: In this article, Fowler and Smith outline the importance of endogenous buffer systems to limiting the spatial and temporal spread of a Ca2+ signal in the highly controlled dyadic cleft.
Journal ArticleDOI
Self-Organization of Functional Coupling between Membrane and Calcium Clock in Arrested Human Sinoatrial Nodal Cells in Response to Camp
Kenta Tsutsui,Oliver Monfredi,Syevda Sirenko,Rostialav Bychkov,Larissa A. Maltseva,Mary S. Kim,Bruce D. Ziman,Kirill V. Tarasov,Mingyi Wang,Alexander V. Maltsev,Jaclyn A. Brennan,Igor R. Efimov,Michael D. Stern,Victor A. Maltsev,Edward G. Lakatta +14 more
Journal ArticleDOI
ARA290, A Small Non-Hematopoietic Peptide Derived From Erythropoietin, Prolongs Healthspan And Attenuates Age-Associated Declines In The Heart's Structure And Function
Alay Nanavati,Jack M. Moen,Jessie Axsom,Melissa Krawczyk,Natalia Petrashevskaya,Max Beyman,Christopher Ramirez,Irene Alfaras,Sarah J. Mitchell,Michel Bernier,Christopher H. Morrell,Steven J. Sollott,Magdalena Juhaszova,Rafael deCabo,Edward G. Lakatta +14 more
TL;DR: This study aims to establish a causative mechanism behind chronic inflammation in patients with a history of prior heart disease and aims to tease out the mechanisms leading to decline in quality of life.