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George Bartzokis
Researcher at University of California, Los Angeles
Publications - 143
Citations - 18062
George Bartzokis is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: White matter & Dementia. The author has an hindex of 66, co-authored 136 publications receiving 16041 citations. Previous affiliations of George Bartzokis include UCLA Medical Center & West Los Angeles College.
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Journal ArticleDOI
The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods.
Clifford R. Jack,Matt A. Bernstein,Nick C. Fox,Paul M. Thompson,Gene E. Alexander,Danielle J Harvey,Bret J. Borowski,Paula J. Britson,Jennifer L. Whitwell,Chadwick P. Ward,Anders M. Dale,Joel P. Felmlee,Jeffrey L. Gunter,Derek L. G. Hill,Ronald J. Killiany,Norbert Schuff,Sabrina Fox-Bosetti,Chen Lin,Colin Studholme,Charles DeCarli,Gunnar Krueger,Heidi A. Ward,Gregory J. Metzger,Katherine T. Scott,Richard Philip Mallozzi,Daniel J. Blezek,Joshua Levy,Josef Phillip Debbins,Adam S. Fleisher,Marilyn S. Albert,Robert C. Green,George Bartzokis,Gary H. Glover,John P. Mugler,Michael W. Weiner +34 more
TL;DR: The approach taken in ADNI to standardization across sites and platforms of the MRI protocol, postacquisition corrections, and phantom‐based monitoring of all scanners could be used as a model for other multisite trials.
Journal ArticleDOI
Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer’s disease
TL;DR: A hypothetical model of Alzheimer's disease as a uniquely human brain disorder rooted in its exceptional process of myelination is presented, offering a framework that explains the anatomical distribution and progressive course of AD pathology, some of the failures of promising therapeutic interventions, and suggests further testable hypotheses as well as novel approaches for intervention efforts.
Journal ArticleDOI
Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
Yasser Iturria-Medina,Roberto C. Sotero,Paule-Joanne Toussaint,José María Mateos-Pérez,Alan C. Evans,Michael W. Weiner,Paul S. Aisen,Ronald C. Petersen,Clifford R. Jack,William J. Jagust,John Q. Trojanowki,Arthur W. Toga,Laurel A. Beckett,Robert C. Green,Andrew J. Saykin,John C. Morris,Leslie M. Shaw,Zaven S. Khachaturian,Greg Sorensen,Lew Kuller,Marc Raichle,Steven M. Paul,Peter Davies,Howard Fillit,Franz Hefti,Davie Holtzman,M. Marcel Mesulam,William Z. Potter,Peter J. Snyder,Adam Schwartz,T. J. Montine,Ronald G. Thomas,Michael C. Donohue,Sarah Walter,Devon Gessert,Tamie Sather,Gus Jiminez,Danielle J Harvey,Matt A. Bernstein,Nick C. Fox,Paul M. Thompson,Norbert Schuff,Bret J. Borowski,Jeff Gunter,M. L. Senjem,Prashanthi Vemuri,David T.W. Jones,Kejal Kantarci,Chad Ward,Robert A. Koeppe,Norm Foster,Eric M. Reiman,Kewei Chen,Chet Mathis,Susan M. Landau,Nigel J. Cairns,Erin Householder,Lisa Taylor-Reinwald,Virginia M.-Y. Lee,Magdalena Korecka,Michal J. Figurski,Karen Crawford,Scott C. Neu,Tatiana Foroud,Steven G. Potkin,Li Shen,Kelley Faber,Sungeun Kim,Kwangsik Nho,Leon J. Thal,Neil Buckholtz,M.S. Albert,Richard Frank,John K. Hsiao,Jeffrey Kaye,Joseph F. Quinn,Betty Lind,Raina Carter,Sara Dolen,Lon S. Schneider,Sonia Pawluczyk,Mauricio Beccera,Liberty Teodoro,Bryan M. Spann,James B. Brewer,Helen Vanderswag,Adam S. Fleisher,Judith L. Heidebrink,Joanne L. Lord,Sara S. Mason,Colleen S. Albers,David S. Knopman,Kris Johnson,Rachelle S. Doody,Javier Villanueva-Meyer,Munir Chowdhury,Susan Rountree,Mimi Dang,Yaakov Stern,Lawrence S. Honig,Karen L. Bell,Beau M. Ances,Maria Carroll,Sue Leon,Mark A. Mintun,Stacy Schneider,Angela Oliver,Daniel C. Marson,Randall Griffith,David Glenn Clark,David S. Geldmacher,John C. Brockington,Erik D. Roberson,Hillel Grossman,Effie M. Mitsis,Leyla de Toledo-Morrell,Raj C. Shah,Ranjan Duara,Daniel Varon,Maria T. Greig,Peggy Roberts,Marilyn S. Albert,Chiadi U. Onyike,Daniel D'Agostino,Stephanie Kielb,James E. Galvin,Brittany Cerbone,Christina A. Michel,Henry Rusinek,Mony J. de Leon,Lidia Glodzik,Susan De Santi,P. Murali Doraiswamy,Jeffrey R. Petrella,Terence Z. Wong,Steven E. Arnold,Jason Karlawish,David A. Wolk,Charles D. Smith,Greg Jicha,Peter A. Hardy,Partha Sinha,Elizabeth Oates,Gary R. Conrad,Oscar L. Lopez,MaryAnn Oakley,Donna M. Simpson,Anton P. Porsteinsson,Bonnie S. Goldstein,Kim Martin,Kelly M. Makino,M. Saleem Ismail,Connie Brand,Ruth A. Mulnard,Gaby Thai,Catherine Mc-Adams-Ortiz,Kyle B. Womack,Dana Mathews,Mary Quiceno,Ramon Diaz-Arrastia,Richard V. King,Myron F. Weiner,Kristen Martin-Cook,Michael D. Devous,Allan I. Levey,James J. Lah,Janet S. Cellar,Jeffrey M. Burns,Heather Anderson,Russell H. Swerdlow,Liana G. Apostolova,Kathleen Tingus,Ellen Woo,Daniel H.S. Silverman,Po H. Lu,George Bartzokis,Neill R. Graff-Radford,Francine Parfitt,Tracy Kendall,Heather Johnson,Martin R. Farlow,Annmarie Hake,Brandy R. Matthews,Scott Herring,Cynthia Hunt,Christopher H. van Dyck,Richard E. Carson,Martha G. MacAvoy,Howard Chertkow,Howard Bergman,Chris Hosein,Sandra E. Black,Bojana Stefanovic,Curtis Caldwell,Ging-Yuek Robin Hsiung,Howard Feldman,Benita Mudge,Michele Assaly,Andrew Kertesz,John Rogers,Charles Bernick,Donna Munic,Diana R. Kerwin,M.-Marsel Mesulam,Kristine Lipowski,Chuang Kuo Wu,Nancy Johnson,Carl H. Sadowsky,Walter Martinez,Teresa Villena,Raymond Scott Turner,Kathleen Johnson,Brigid Reynolds,Reisa A. Sperling,Keith A. Johnson,Gad A. Marshall,Meghan Frey,Barton Lane,Allyson Rosen,Jared R. Tinklenberg,Marwan N. Sabbagh,Christine M. Belden,Sandra Jacobson,Sherye A. Sirrel,Neil W. Kowall,Ronald J. Killiany,Andrew E. Budson,Alexander Norbash,Patricia Lynn Johnson,Joanne S. Allard,Alan J. Lerner,Paula Ogrocki,Leon Hudson,Evan Fletcher,Owen Carmichael,John M Olichney,Charles DeCarli,Smita Kittur,Michael Borrie,T. Y. Lee,Rob Bartha,Sterling C. Johnson,Sanjay Asthana,Cynthia M. Carlsson,Steven Potkin,Adrian Preda,Dana Nguyen,Pierre N. Tariot,Stephanie Reeder,Vernice Bates,Horacio Capote,Michelle Rainka,Douglas W. Scharre,Maria Kataki,Anahita Adeli,Earl A. Zimmerman,Dzintra Celmins,Alice D. Brown,Godfrey D. Pearlson,Karen Blank,Karen E. Anderson,Robert B. Santulli,Tamar J. Kitzmiller,Eben S. Schwartz,Kaycee M. Sink,Jeff D. Williamson,Pradeep Garg,Franklin Watkins,Brian R. Ott,Henry W. Querfurth,Geoffrey Tremont,Stephen Salloway,Paul Malloy,Stephen Correia,Howard J. Rosen,Bruce L. Miller,Jacobo Mintzer,Kenneth M. Spicer,David Bachman,Elizabether Finger,Stephen H. Pasternak,Irina Rachinsky,Dick J. Drost,Nunzio Pomara,Raymundo Hernando,Antero Sarrael,Susan K. Schultz,Laura L. Boles Ponto,Hyungsub Shim,Karen Elizabeth Smith,Norman R. Relkin,Gloria Chaing,Lisa Raudin,Amanda Smith,Kristin Fargher,Balebail Ashok Raj,Thomas C. Neylan,Jordan Grafman,Melissa Davis,Rosemary H Morrison,Jacqueline Hayes,Shannon Finley,Karl E. Friedl,Debra A. Fleischman,Konstantinos Arfanakis,Olga James,Dino Massoglia,J. Jay Fruehling,Sandra Harding,Elaine R. Peskind,Eric C. Petrie,Gail Li,Jerome A. Yesavage,Joy L. Taylor,Ansgar J. Furst +314 more
TL;DR: Imaging results suggest that intra-brain vascular dysregulation is an early pathological event during disease development, suggesting early memory deficit associated with the primary disease factors.
Journal ArticleDOI
Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study.
TL;DR: The changes in white matter suggest that the adult brain is in a constant state of change roughly defined as periods of maturation continuing into the fifth decade of life followed by degeneration.
Journal ArticleDOI
Alzheimer's disease as homeostatic responses to age-related myelin breakdown
TL;DR: This work delineates empirically testable mechanisms of action for genes underlying FAD and LOAD and provides "upstream" treatment targets and reframes key observations such as axonal transport disruptions, formation of axonal swellings/sphenoids and neuritic plaques, and proteinaceous deposits as by-products of homeostatic myelin repair processes.