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I. M. Heid
Researcher at KORA Organics
Publications - 8
Citations - 1161
I. M. Heid is an academic researcher from KORA Organics. The author has contributed to research in topics: Genome-wide association study & Childhood obesity. The author has an hindex of 6, co-authored 8 publications receiving 1113 citations.
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Journal ArticleDOI
A common genetic variant is associated with adult and childhood obesity.
Alan Herbert,Norman P. Gerry,Matthew B. McQueen,I. M. Heid,Arne Pfeufer,Thomas Illig,H.-Erich Wichmann,H.-Erich Wichmann,Thomas Meitinger,David J. Hunter,David J. Hunter,Frank B. Hu,Frank B. Hu,Graham A. Colditz,Anke Hinney,Johannes Hebebrand,Kerstin Koberwitz,Kerstin Koberwitz,Xiaofeng Zhu,Richard S. Cooper,Kristin G. Ardlie,Helen N. Lyon,Helen N. Lyon,Helen N. Lyon,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Nan M. Laird,Marc E. Lenburg,Christoph Lange,Christoph Lange,Michael F. Christman +31 more
TL;DR: A dense whole-genome scan of DNA samples from the Framingham Heart Study participants was used to identify a common genetic variant near the INSIG2 gene associated with obesity, suggesting that common genetic polymorphisms are important determinants of obesity.
Journal ArticleDOI
Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations
Yukinori Okada,Xueling Sim,Xueling Sim,Min Jin Go,Jer-Yuarn Wu,Jer-Yuarn Wu,Dongfeng Gu,Fumihiko Takeuchi,Atsushi Takahashi,Shiro Maeda,Tatsuhiko Tsunoda,Peng Chen,Su Chi Lim,Su Chi Lim,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong,Jianjun Liu,Terri L. Young,Tin Aung,Tin Aung,Mark Seielstad,Yik Ying Teo,Yik Ying Teo,Young-Jin Kim,Jong-Young Lee,Bok Ghee Han,Daehee Kang,Chien Hsiun Chen,Chien Hsiun Chen,Fuu Jen Tsai,Li-Ching Chang,S. J. Fann,Hao Mei,Dabeeru C. Rao,James E. Hixson,Shufeng Chen,Tomohiro Katsuya,Motohide Isono,Toshio Ogihara,Toshio Ogihara,John C. Chambers,Weihua Zhang,Jaspal S. Kooner,E Albrecht,Kazuhiko Yamamoto,Michiaki Kubo,Yusuke Nakamura,Kamatani Naoyuki,Norihiro Kato,Jiang He,Yuan-Tsong Chen,Yoon Shin Cho,E-Shyong Tai,Toshihiro Tanaka,Graham M. Lord,P. van der Harst,Debbie A Lawlor,Jobanpreet Sehmi,Daniel P. Gale,Mark N. Wass,Kourosh R. Ahmadi,Stephan J. L. Bakker,Jacqui Beckmann,Hjg Bilo,Murielle Bochud,Morris J. Brown,M. J. Caulfield,Jmc Connell,H.T. Cook,Ioana Cotlarciuc,George Davey Smith,R. de Silva,G. Deng,Olivier Devuyst,L. D. Dikkeschei,N. Dimkovic,M. Dockrell,Anna F. Dominiczak,S Ebrahim,Thomas Eggermann,Martin Farrall,L Ferrucci,Juergen Floege,Nita G. Forouhi,Ron T. Gansevoort,X. Han,Bo Hedblad,J. J. van der Heide,Bouke G. Hepkema,Maria P. Hernandez-Fuentes,Elina Hyppönen,Toby Johnson,P. E. De Jong,Nanno Kleefstra,Vasiliki Lagou,Marta Lapsley,Yun Li,Ruth J. F. Loos,Jian'an Luan,Karin Luttropp,Céline Maréchal,Olle Melander,Patricia B. Munroe,Louise Nordfors,Afshin Parsa,Leena Peltonen,B.W.J.H. Penninx,Esperanza Perucha,A Pouta,Inga Prokopenko,Paul Roderick,Aimo Ruokonen,Nilesh J. Samani,Serena Sanna,Martin Schalling,David Schlessinger,Georg Schlieper,Marc A. Seelen,A. R. Shuldiner,Marketa Sjögren,J.H. Smit,Harold Snieder,Nicola Soranzo,Tim D. Spector,Peter Stenvinkel,Michael J.E. Sternberg,R. Swaminathan,L.J. Ubink-Veltmaat,Manuela Uda,Peter Vollenweider,Chris Wallace,Dawn M. Waterworth,Klaus Zerres,Gérard Waeber,Nicholas J. Wareham,Patrick H. Maxwell,Mark I. McCarthy,M-R Jarvelin,Vincent Mooser,G. Abecasis,Liz Lightstone,Jemima Scott,Gerjan Navis,Paul Elliott,Anna Köttgen,C. Pattaro,Carsten A. Böger,Christian Fuchsberger,Matthias Olden,Nicole L. Glazer,X. Gao,Qiong Yang,Albert V. Smith,Jeffery R. O'Connell,Man Li,H. Schmidt,A Isaacs,Shamika Ketkar,Shih-Jen Hwang,Andrew D. Johnson,Abbas Dehghan,A. Teumer,Guillaume Paré,Elizabeth J. Atkinson,Tanja Zeller,Kurt Lohman,Marilyn C. Cornelis,Nicole Probst-Hensch,Florian Kronenberg,A Tönjes,Caroline Hayward,Thor Aspelund,G. Eiriksdottir,L. J. Launer,T.B. Harris,Evandine Rampersaud,B. D. Mitchell,D.E. Arking,Eric Boerwinkle,Maksim Struchalin,Margherita Cavalieri,AB Singleton,Francesco Giallauria,Jeffrey Metter,I. H. de Boer,Talin Haritunians,Thomas Lumley,David S. Siscovick,Bruce M. Psaty,M. C. Zillikens,B.A. Oostra,Mary F. Feitosa,M. A. Province,M. De Andrade,Stephen T. Turner,Arne Schillert,Anette-G. Ziegler,Philipp S. Wild,Renate B. Schnabel,Sandra Wilde,Thomas Münzel,Tennille S. Leak,Thomas Illig,N. Klopp,Christine Meisinger,Heinz Erich Wichmann,Wolfgang Koenig,Lina Zgaga,Tatijana Zemunik,Ivana Kolcic,Cosetta Minelli,Frank B. Hu,Johansson,Wilmar Igl,Ghazal Zaboli,Sarah H. Wild,A. F. Wright,Hannah Campbell,David Ellinghaus,Stuart L. Schreiber,Y S Aulchenko,Janine F. Felix,F. Rivadeneira,A.G. Uitterlinden,A. Hofman,Medea Imboden,Dorothea Nitsch,Anita Brandstätter,Barbara Kollerits,Lyudmyla Kedenko,Reedik Mägi,Michael Stumvoll,Peter Kovacs,Mladen Boban,Sharon Campbell,Karlhans Endlich,Henry Völzke,Heyo K. Kroemer,Matthias Nauck,Uwe Völker,Ozren Polašek,Veronique Vitart,Sunita Badola,Alex Parker,Paul M. Ridker,Sharon L.R. Kardia,Stefan Blankenberg,Yongmei Liu,G. C. Curhan,Andre Franke,Tatiana Rochat,B. Paulweber,W. Wang,Vilmundur Gudnason,Josef Coresh,Reinhold E. Schmidt,Michael G. Shlipak,C M van Duijn,Ingrid B. Borecki,Bernhard K. Krämer,Igor Rudan,Ulf Gyllensten,J.F. Wilson,J. C. M. Witteman,Peter P. Pramstaller,Rainer Rettig,Nicholas D. Hastie,Daniel I. Chasman,W. H. Kao,I. M. Heid,Caroline S. Fox,Jan Krumsiek,Claudia Hundertmark,Giorgio Pistis,Daniela Ruggiero,M. O'seaghdha,T. Haller,Z. Kutalik,Julia Shi,P. S. Middelberg,Angelo L. Gaffo,Nicola Pirastu,Guo Li,Jennifer E. Huffman,Loic Yengo,Jing Hua Zhao,Ayse Demirkan,M. F. Feitosa,Xuan Liu,Giovanni Malerba,Lorna M. Lopez,Xinzhong Li,Marcus E. Kleber,Andrew A. Hicks,Ilja M. Nolte,Åsa Johansson,Federico Murgia,J F Peden,Maristella Steri,Albert Tenesa,Perttu Salo,Massimo Mangino,Lynda M. Rose,Terho Lehtimäki,Owen M. Woodward,Adrienne Tin,Craig Muller,Christopher Oldmeadow,Margus Putku,Darina Czamara,Peter Kraft,Laura Frogheri,Gian Andri Thun,Anne Grotevendt,Gauti Kjartan Gislason,Patrick F. McArdle,Michael Schallert,N. G. Martin,Grant W. Montgomery,David R. Jacobs,Kiang Liu,Pio D'Adamo,S. Ulivi,Jerome I. Rotter,P. Navaro,B. Balkau,Philippe Froguel,Tõnu Esko,Andres Salumets,Kay-Tee Khaw,Claudia Langenberg,Aldi T. Kraja,Qunyuan Zhang,Rodney J. Scott,Elizabeth G. Holliday,Elin Org,Margus Viigimaa,Stefania Bandinelli,Jeffery Metter,Antonio Lupo,Elisabetta Trabetti,Rossella Sorice,Angela Döring,Eva Lattka,Konstantin Strauch,Fabian J. Theis,M. Waldenberger,G. Davies,Alan J. Gow,Marcel Bruinenberg,Ronald P. Stolk,Winkelmann Br,B O Boehm,Susanne Lucae,G. Curhan,Poorva Mudgal,Robert M. Plenge,Laura Portas,Ivana Persico,Mirna Kirin,I. Mateo Leach,W. H. Van Gilst,Anuj Goel,Halit Ongen,A. von Eckardstein,Francesco Cucca,Ramaiah Nagaraja,Maria Grazia Piras,Claudia Schurmann,Klemens Budde,Florian Ernst,Susan M. Farrington,Evropi Theodoratou,A. Jula,M. Perola,V. Salomaa,So-Youn Shin,Cinzia Sala,Mika Kähönen,Jorma Viikari,Christian Hengstenberg,Christopher P. Nelson,James F. Meschia,Michael A. Nalls,Pankaj Sharma,Andrew B. Singleton,Michel Burnier,John Attia,Maris Laan,Hans L. Hillege,Stefan Kloiber,Hyon K. Choi,Mario Pirastu,Silvia Tore,John Whitfield,Myriam Fornage,Paolo Gasparini,David S. Siscovick,Nabila Bouatia-Naji,Andres Metspalu,Ingrid B. Borecki,Giovanni Gambaro,Ian J. Deary,Bruce H. R. Wolffenbuttel,W. März,Hugh Watkins,Sabine Schipf,Malcolm G. Dunlop,S. Ripatti,Daniela Toniolo,Olli T. Raitakari,Marina Ciullo,Mark J. Caulfield,C Gieger +414 more
TL;DR: A meta-analysis of genome-wide association studies for kidney function–related traits, including 71,149 east Asian individuals from 18 studies in 11 population-, hospital- or family-based cohorts, conducted as part of the Asian Genetic Epidemiology Network (AGEN), identified 17 loci newly associated with kidney function-related traits.
Journal ArticleDOI
Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys
I. M. Heid,Caren Vollmert,Anke Hinney,Angela Döring,Frank Geller,Hannelore Löwel,Heinz Erich Wichmann,Thomas Illig,Johannes Hebebrand,Florian Kronenberg +9 more
TL;DR: This study confirms previous findings of a meta-analysis that the relatively infrequent G/A genotype of the V103I MC4R polymorphism is negatively associated with above average weight and obesity in population based original data of 7937 participants, and extends previous findings by showing for the first time a significantly lower BMI in individuals carrying the infrequent allele of thisMC4R variant.
Genome-wide meta-analysis of common variant differences between men and women
Vesna Boraska,Ana Jerončić,Vincenza Colonna,Lorraine Southam,Dale R. Nyholt,N W Rayner,John R. B. Perry,Daniela Toniolo,Eva Albrecht,Wei Ang,Stefania Bandinelli,Maja Barbalić,Inês Barroso,Jacques S. Beckmann,Reiner Biffar,Dorret I. Boomsma,Harry Campbell,Tanguy Corre,Jeanette Erdmann,Tõnu Esko,Krista Fischer,Nora Franceschini,Timothy M. Frayling,Giorgia Girotto,Juan R. González,Tamara B. Harris,A. C. Heath,I. M. Heid,W. Hoffmann,Albert Hofman,Momoko Horikoshi,Jing Hua Zhao,Anne U. Jackson,Jouke-Jan Hottenga,A. Jula,Mika Kähönen,Kay-Tee Khaw,Lambertus A. Kiemeney,N Klopp,Zoltán Kutalik,Vasiliki Lagou,Lenore J. Launer,Terho Lehtimäki,Mathieu Lemire,M. L. Lokki,Christina Loley,Jian'an Luan,Massimo Mangino,I. Mateo Leach,S. E. Medland,Evelin Mihailov,Grant W. Montgomery,Gerjan Navis,John P. Newnham,Nieminen,Aarno Palotie,Kalliope Panoutsopoulou,Annette Peters,Nicola Pirastu,Ozren Polasek,Karola Rehnström,Samuli Ripatti,Graham R S Ritchie,Fernando Rivadeneira,Antonietta Robino,Nilesh J. Samani,So-Youn Shin,Juha Sinisalo,J.H. Smit,Nicole Soranzo,Lisette Stolk,Dorine W. Swinkels,Toshiko Tanaka,Alexander Teumer,A Tönjes,Michela Traglia,Jaakko Tuomilehto,Armand Valsesia,W. H. Van Gilst,J.B. van Meurs,Albert V. Smith,Jorma Viikari,J.M. Vink,G. Waeber,Nicole M. Warrington,E. Widen,Gonneke Willemsen,A. F. Wright,Brent W. Zanke,Lina Zgaga,Michael Boehnke,Adamo Pio d'Adamo,E.J.C. de Geus,W. Demerath,M. den Heijer,Johan G. Eriksson,Luigi Ferrucci,Christian Gieger,Vilmundur Gudnason,Caroline Hayward,Christian Hengstenberg,Thomas J. Hudson,Marjo-Riitta Järvelin,Manolis Kogevinas,Ruth J. F. Loos,Nicholas G. Martin,Andres Metspalu,Craig E. Pennell,B.W.J.H. Penninx,Marcus Perola,Olli T. Raitakari,Veikko Salomaa,Stefan Schreiber,Heribert Schunkert,Tim D. Spector,Michael Stumvoll,André G. Uitterlinden,S. Ulivi,P. van der Harst,Peter Vollenweider,Henry Völzke,Nicholas J. Wareham,H. E. Wichmann,James F. Wilson,Igor Rudan,Yali Xue,Eleftheria Zeggini +126 more
TL;DR: This paper conducted a large-scale genome-wide association scan (GWAS) meta-analysis across 51 studies, comprising overall 114 863 individuals (61 094 women and 53 769 men) of European ancestry and 2 623 828 common (minor allele frequency > 0.05) single-nucleotide polymorphisms (SNPs).