C
Chloe Fawns-Ritchie
Researcher at University of Edinburgh
Publications - 54
Citations - 3331
Chloe Fawns-Ritchie is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Medicine & Mental health. The author has an hindex of 16, co-authored 46 publications receiving 2120 citations. Previous affiliations of Chloe Fawns-Ritchie include University of Glasgow.
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Journal ArticleDOI
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Gail Davies,Max Lam,Sarah E. Harris,Joey W. Trampush,Michelle Luciano,W. David Hill,Saskia P. Hagenaars,Saskia P. Hagenaars,Stuart J. Ritchie,Riccardo E. Marioni,Chloe Fawns-Ritchie,David C. Liewald,Judith A. Okely,Ari Ahola-Olli,Catriona L. K. Barnes,Lars Bertram,Joshua C. Bis,Katherine E. Burdick,Katherine E. Burdick,Katherine E. Burdick,Andrea Christoforou,Pamela DeRosse,Srdjan Djurovic,Srdjan Djurovic,Thomas Espeseth,Stella G. Giakoumaki,Sudheer Giddaluru,Daniel E. Gustavson,Caroline Hayward,Edith Hofer,M. Arfan Ikram,Robert Karlsson,Emma Knowles,Jari Lahti,Markus Leber,Shuo Li,Karen A. Mather,Ingrid Melle,Ingrid Melle,Derek W. Morris,Christopher Oldmeadow,Teemu Palviainen,Antony Payton,Raha Pazoki,Katja Petrovic,Chandra A. Reynolds,Muralidharan Sargurupremraj,Markus Scholz,Jennifer A. Smith,Albert V. Smith,Natalie Terzikhan,Natalie Terzikhan,Anbupalam Thalamuthu,Stella Trompet,Sven J. van der Lee,Erin B. Ware,Beverly Gwen Windham,Margaret J. Wright,Jingyun Yang,Jin Yu,David Ames,David Ames,Najaf Amin,Philippe Amouyel,Ole A. Andreassen,Nicola J. Armstrong,Amelia A. Assareh,John Attia,Deborah K. Attix,Dimitrios Avramopoulos,David A. Bennett,Anne C. Böhmer,Patricia A. Boyle,Henry Brodaty,Harry Campbell,Tyrone D. Cannon,Elizabeth T. Cirulli,Eliza Congdon,Emily Drabant Conley,Janie Corley,Simon R. Cox,Anders M. Dale,Abbas Dehghan,Danielle M. Dick,Dwight Dickinson,Johan G. Eriksson,Johan G. Eriksson,Evangelos Evangelou,Evangelos Evangelou,Jessica D. Faul,Ian Ford,Nelson A. Freimer,He Gao,Ina Giegling,Nathan A. Gillespie,Scott D. Gordon,R. F. Gottesman,Michael Griswold,Vilmundur Gudnason,Tamara B. Harris,Annette M. Hartmann,Alex Hatzimanolis,Alex Hatzimanolis,Gerardo Heiss,Elizabeth G. Holliday,Peter K. Joshi,Mika Kähönen,Sharon L.R. Kardia,Ida K. Karlsson,Luca Kleineidam,Luca Kleineidam,Luca Kleineidam,David S. Knopman,Nicole A. Kochan,Bettina Konte,John B.J. Kwok,John B.J. Kwok,Stephanie Le Hellard,Teresa Lee,Terho Lehtimäki,Shu-Chen Li,Shu-Chen Li,Tian Liu,Marisa Koini,Edythe D. London,Will Longstreth,Oscar L. Lopez,Anu Loukola,Tobias Luck,Astri J. Lundervold,Anders Lundquist,Leo-Pekka Lyytikäinen,Nicholas G. Martin,Grant W. Montgomery,Grant W. Montgomery,Alison D. Murray,Alison D. Murray,Anna C. Need,Raymond Noordam,Lars Nyberg,William Ollier,Goran Papenberg,Goran Papenberg,Alison Pattie,Ozren Polasek,Russell A. Poldrack,Bruce M. Psaty,Bruce M. Psaty,Simone Reppermund,Steffi G. Riedel-Heller,Richard J. Rose,Jerome I. Rotter,Panos Roussos,Panos Roussos,Suvi P. Rovio,Yasaman Saba,Fred W. Sabb,Perminder S. Sachdev,Claudia L. Satizabal,Claudia L. Satizabal,Matthias Schmid,Rodney J. Scott,Matthew A. Scult,Jeannette Simino,P. Eline Slagboom,Nikolaos Smyrnis,Nikolaos Smyrnis,Aicha Soumare,Nikos C. Stefanis,Nikos C. Stefanis,David J. Stott,Richard E. Straub,Kjetil Sundet,Adele M. Taylor,Kent D. Taylor,Ioanna Tzoulaki,Ioanna Tzoulaki,Christophe Tzourio,Christophe Tzourio,André G. Uitterlinden,Veronique Vitart,Aristotle N. Voineskos,Jaakko Kaprio,Jaakko Kaprio,Michael Wagner,Michael Wagner,Holger Wagner,Leonie Weinhold,K. Hoyan Wen,Elisabeth Widen,Qiong Yang,Wei Zhao,Hieab H.H. Adams,Dan E. Arking,Robert M. Bilder,Panos Bitsios,Eric Boerwinkle,Eric Boerwinkle,Ornit Chiba-Falek,Aiden Corvin,Philip L. De Jager,Philip L. De Jager,Stéphanie Debette,Stéphanie Debette,Gary Donohoe,Paul Elliott,Annette L. Fitzpatrick,Michael Gill,David C. Glahn,Sara Hägg,Narelle K. Hansell,Ahmad R. Hariri,M. Kamran Ikram,J. Wouter Jukema,Eero Vuoksimaa,Matthew C. Keller,William S. Kremen,Lenore J. Launer,Ulman Lindenberger,Aarno Palotie,Aarno Palotie,Nancy L. Pedersen,Neil Pendleton,David J. Porteous,Katri Räikkönen,Olli T. Raitakari,Alfredo Ramirez,Alfredo Ramirez,Ivar Reinvang,Igor Rudan,Dan Rujescu,Reinhold Schmidt,Helena Schmidt,Peter W. Schofield,Peter R. Schofield,Peter R. Schofield,John M. Starr,Vidar M. Steen,Julian N. Trollor,Steven T. Turner,Cornelia M. van Duijn,Arno Villringer,Arno Villringer,Daniel R. Weinberger,David R. Weir,James F. Wilson,Anil K. Malhotra,Anil K. Malhotra,Andrew M. McIntosh,Catharine R. Gale,Sudha Seshadri,Sudha Seshadri,Sudha Seshadri,Thomas H. Mosley,Jan Bressler,Todd Lencz,Todd Lencz,Ian J. Deary +257 more
TL;DR: In this paper, the authors combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16-102) and find 148 genome-wide significant independent loci associated with general cognitive function.
Journal ArticleDOI
Genome-wide association study of cognitive functions and educational attainment in UK Biobank ( N =112 151)
Gail Davies,Riccardo E. Marioni,Riccardo E. Marioni,David C. Liewald,WD Hill,Saskia P. Hagenaars,Sarah E. Harris,Stuart J. Ritchie,Michelle Luciano,Chloe Fawns-Ritchie,Donald M. Lyall,Breda Cullen,Simon R. Cox,Caroline Hayward,David J. Porteous,Jonathan Evans,Andrew M. McIntosh,John Gallacher,Nicholas John Craddock,Jill P. Pell,Daniel J. Smith,Catharine R. Gale,Catharine R. Gale,Ian J. Deary +23 more
TL;DR: The genome-wide significant single-nucleotide polymorphism (SNP)-based associations in 20 genomic regions, and significant gene-based findings in 46 regions are reported, including findings in the ATXN2, CYP2DG, APBA1 and CADM2 genes.
Journal ArticleDOI
Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N = 112 151) and 24 GWAS consortia.
Saskia P. Hagenaars,Sarah E. Harris,Sarah E. Harris,Gail Davies,WD Hill,David C. Liewald,Stuart J. Ritchie,Riccardo E. Marioni,Riccardo E. Marioni,Riccardo E. Marioni,Chloe Fawns-Ritchie,Breda Cullen,Rainer Malik,Bradford B. Worrall,Cathie Sudlow,Cathie Sudlow,Joanna M. Wardlaw,John Gallacher,Jill P. Pell,Andrew M. McIntosh,Daniel J. Smith,Catharine R. Gale,Catharine R. Gale,Ian J. Deary +23 more
TL;DR: Findings indicate that a substantial level of pleiotropy exists between cognitive abilities and many human mental and physical health disorders and traits and that it can be used to predict phenotypic variance across samples.
Journal ArticleDOI
Mental health before and during the COVID-19 pandemic in two longitudinal UK population cohorts.
Alex S. F. Kwong,Rebecca M. Pearson,Mark Adams,Kate Northstone,Kate Tilling,Daniel J. Smith,Chloe Fawns-Ritchie,Helen Bould,Naomi Warne,Stanley Zammit,David Gunnell,Paul Moran,Nadia Micali,Abraham Reichenberg,Matthew Hickman,Dheeraj Rai,Simon Haworth,Archie Campbell,Drew Altschul,Robin Flaig,Andrew M. McIntosh,Debbie A Lawlor,David J. Porteous,Nicholas J. Timpson +23 more
TL;DR: In both studies, anxiety and depression during the pandemic was greater in younger members, women, those with pre-existing mental/physical health conditions and individuals in socioeconomic adversity, even when controlling for pre-pandemicxiety and depression.
Journal ArticleDOI
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism
Michelle Luciano,Saskia P. Hagenaars,Saskia P. Hagenaars,Gail Davies,WD Hill,Toni-Kim Clarke,Masoud Shirali,Sarah E. Harris,Sarah E. Harris,Riccardo E. Marioni,Riccardo E. Marioni,David C. Liewald,Chloe Fawns-Ritchie,Mark Adams,David M. Howard,Cathryn M. Lewis,Catharine R. Gale,Catharine R. Gale,Andrew M. McIntosh,Ian J. Deary +19 more
TL;DR: Analysis of 329,000 individuals in the UK Biobank identifies 116 loci associated with neuroticism that are enriched in neuronal genesis and differentiation pathways, and genetic correlations between neuroticism and other mental health traits are elucidated.