P
Peter W. Schofield
Researcher at University of Newcastle
Publications - 101
Citations - 6404
Peter W. Schofield is an academic researcher from University of Newcastle. The author has contributed to research in topics: Population & Poison control. The author has an hindex of 34, co-authored 100 publications receiving 5745 citations. Previous affiliations of Peter W. Schofield include Ministry of Health (New South Wales) & John Hunter Hospital.
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Journal ArticleDOI
Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
Ming-Xin Tang,Diane M. Jacobs,Yaakov Stern,Karen Marder,Peter W. Schofield,Barry J. Gurland,Howard Andrews,Richard Mayeux +7 more
TL;DR: Oestrogen use in postmenopausal women may delay the onset and decrease the risk of Alzheimer's disease and Prospective studies are needed to establish the dose and duration required to provide this benefit and to assess its safety in elderly post menopause women.
Journal ArticleDOI
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Gail Davies,Max Lam,Sarah E. Harris,Joey W. Trampush,Michelle Luciano,W. David Hill,Saskia P. Hagenaars,Saskia P. Hagenaars,Stuart J. Ritchie,Riccardo E. Marioni,Chloe Fawns-Ritchie,David C. Liewald,Judith A. Okely,Ari Ahola-Olli,Catriona L. K. Barnes,Lars Bertram,Joshua C. Bis,Katherine E. Burdick,Katherine E. Burdick,Katherine E. Burdick,Andrea Christoforou,Pamela DeRosse,Srdjan Djurovic,Srdjan Djurovic,Thomas Espeseth,Stella G. Giakoumaki,Sudheer Giddaluru,Daniel E. Gustavson,Caroline Hayward,Edith Hofer,M. Arfan Ikram,Robert Karlsson,Emma Knowles,Jari Lahti,Markus Leber,Shuo Li,Karen A. Mather,Ingrid Melle,Ingrid Melle,Derek W. Morris,Christopher Oldmeadow,Teemu Palviainen,Antony Payton,Raha Pazoki,Katja Petrovic,Chandra A. Reynolds,Muralidharan Sargurupremraj,Markus Scholz,Jennifer A. Smith,Albert V. Smith,Natalie Terzikhan,Natalie Terzikhan,Anbupalam Thalamuthu,Stella Trompet,Sven J. van der Lee,Erin B. Ware,Beverly Gwen Windham,Margaret J. Wright,Jingyun Yang,Jin Yu,David Ames,David Ames,Najaf Amin,Philippe Amouyel,Ole A. Andreassen,Nicola J. Armstrong,Amelia A. Assareh,John Attia,Deborah K. Attix,Dimitrios Avramopoulos,David A. Bennett,Anne C. Böhmer,Patricia A. Boyle,Henry Brodaty,Harry Campbell,Tyrone D. Cannon,Elizabeth T. Cirulli,Eliza Congdon,Emily Drabant Conley,Janie Corley,Simon R. Cox,Anders M. Dale,Abbas Dehghan,Danielle M. Dick,Dwight Dickinson,Johan G. Eriksson,Johan G. Eriksson,Evangelos Evangelou,Evangelos Evangelou,Jessica D. Faul,Ian Ford,Nelson A. Freimer,He Gao,Ina Giegling,Nathan A. Gillespie,Scott D. Gordon,R. F. Gottesman,Michael Griswold,Vilmundur Gudnason,Tamara B. Harris,Annette M. Hartmann,Alex Hatzimanolis,Alex Hatzimanolis,Gerardo Heiss,Elizabeth G. Holliday,Peter K. Joshi,Mika Kähönen,Sharon L.R. Kardia,Ida K. Karlsson,Luca Kleineidam,Luca Kleineidam,Luca Kleineidam,David S. Knopman,Nicole A. Kochan,Bettina Konte,John B.J. Kwok,John B.J. Kwok,Stephanie Le Hellard,Teresa Lee,Terho Lehtimäki,Shu-Chen Li,Shu-Chen Li,Tian Liu,Marisa Koini,Edythe D. London,Will Longstreth,Oscar L. Lopez,Anu Loukola,Tobias Luck,Astri J. Lundervold,Anders Lundquist,Leo-Pekka Lyytikäinen,Nicholas G. Martin,Grant W. Montgomery,Grant W. Montgomery,Alison D. Murray,Alison D. Murray,Anna C. Need,Raymond Noordam,Lars Nyberg,William Ollier,Goran Papenberg,Goran Papenberg,Alison Pattie,Ozren Polasek,Russell A. Poldrack,Bruce M. Psaty,Bruce M. Psaty,Simone Reppermund,Steffi G. Riedel-Heller,Richard J. Rose,Jerome I. Rotter,Panos Roussos,Panos Roussos,Suvi P. Rovio,Yasaman Saba,Fred W. Sabb,Perminder S. Sachdev,Claudia L. Satizabal,Claudia L. Satizabal,Matthias Schmid,Rodney J. Scott,Matthew A. Scult,Jeannette Simino,P. Eline Slagboom,Nikolaos Smyrnis,Nikolaos Smyrnis,Aicha Soumare,Nikos C. Stefanis,Nikos C. Stefanis,David J. Stott,Richard E. Straub,Kjetil Sundet,Adele M. Taylor,Kent D. Taylor,Ioanna Tzoulaki,Ioanna Tzoulaki,Christophe Tzourio,Christophe Tzourio,André G. Uitterlinden,Veronique Vitart,Aristotle N. Voineskos,Jaakko Kaprio,Jaakko Kaprio,Michael Wagner,Michael Wagner,Holger Wagner,Leonie Weinhold,K. Hoyan Wen,Elisabeth Widen,Qiong Yang,Wei Zhao,Hieab H.H. Adams,Dan E. Arking,Robert M. Bilder,Panos Bitsios,Eric Boerwinkle,Eric Boerwinkle,Ornit Chiba-Falek,Aiden Corvin,Philip L. De Jager,Philip L. De Jager,Stéphanie Debette,Stéphanie Debette,Gary Donohoe,Paul Elliott,Annette L. Fitzpatrick,Michael Gill,David C. Glahn,Sara Hägg,Narelle K. Hansell,Ahmad R. Hariri,M. Kamran Ikram,J. Wouter Jukema,Eero Vuoksimaa,Matthew C. Keller,William S. Kremen,Lenore J. Launer,Ulman Lindenberger,Aarno Palotie,Aarno Palotie,Nancy L. Pedersen,Neil Pendleton,David J. Porteous,Katri Räikkönen,Olli T. Raitakari,Alfredo Ramirez,Alfredo Ramirez,Ivar Reinvang,Igor Rudan,Dan Rujescu,Reinhold Schmidt,Helena Schmidt,Peter W. Schofield,Peter R. Schofield,Peter R. Schofield,John M. Starr,Vidar M. Steen,Julian N. Trollor,Steven T. Turner,Cornelia M. van Duijn,Arno Villringer,Arno Villringer,Daniel R. Weinberger,David R. Weir,James F. Wilson,Anil K. Malhotra,Anil K. Malhotra,Andrew M. McIntosh,Catharine R. Gale,Sudha Seshadri,Sudha Seshadri,Sudha Seshadri,Thomas H. Mosley,Jan Bressler,Todd Lencz,Todd Lencz,Ian J. Deary +257 more
TL;DR: In this paper, the authors combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16-102) and find 148 genome-wide significant independent loci associated with general cognitive function.
Journal ArticleDOI
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)
Gary Davies,Nicola J. Armstrong,J. C. Bis,Jan Bressler,Vincent Chouraki,Vincent Chouraki,Sudheer Giddaluru,Edith Hofer,Carla A. Ibrahim-Verbaas,Mirna Kirin,Jari Lahti,S. J. van der Lee,S. Le Hellard,Tian Liu,Riccardo E. Marioni,Riccardo E. Marioni,Christopher Oldmeadow,Iris Postmus,Albert V. Smith,Jennifer A. Smith,Anbupalam Thalamuthu,Russell Thomson,Veronique Vitart,Jing Wang,Jing Wang,Le Yu,Lina Zgaga,Lina Zgaga,Wei Zhao,Ruth Boxall,Sarah E. Harris,WD Hill,D C Liewald,Michelle Luciano,Hieab H.H. Adams,David Ames,David Ames,Najaf Amin,P. Amouyel,Amelia A. Assareh,Rhoda Au,Rhoda Au,James T. Becker,Alexa S. Beiser,Alexa S. Beiser,Claudine Berr,Claudine Berr,Lars Bertram,Lars Bertram,Eric Boerwinkle,Eric Boerwinkle,Brendan M. Buckley,Harry Campbell,Janie Corley,P. L. De Jager,P. L. De Jager,Carole Dufouil,Johan G. Eriksson,Johan G. Eriksson,Thomas Espeseth,Jessica D. Faul,Ian Ford,Generation Scotland,Rebecca F. Gottesman,Michael Griswold,Vilmundur Gudnason,T.B. Harris,Gerardo Heiss,Albert Hofman,Elizabeth G. Holliday,Jennifer E. Huffman,Sharon L.R. Kardia,Nicole A. Kochan,D. S. Knopman,John B.J. Kwok,John B.J. Kwok,Jean-Charles Lambert,Teresa Lee,Ge Li,Shu-Chen Li,Shu-Chen Li,Marisa Loitfelder,Oscar L. Lopez,Astri J. Lundervold,Astri J. Lundervold,A. Lundqvist,Karen A. Mather,Saira Saeed Mirza,Lars Nyberg,Ben A. Oostra,Aarno Palotie,Aarno Palotie,Goran Papenberg,Goran Papenberg,Alison Pattie,Katja Petrovic,Ozren Polasek,Bruce M. Psaty,Bruce M. Psaty,Paul Redmond,Simone Reppermund,Jerome I. Rotter,Helena Schmidt,Maaike Schuur,Peter W. Schofield,Rodney J. Scott,Vidar M. Steen,David J. Stott,J. C. van Swieten,K. D. Taylor,Julian N. Trollor,Stella Trompet,André G. Uitterlinden,Galit Weinstein,Galit Weinstein,Elisabeth Widen,Beverly G Windham,Johan Wouter Jukema,Alan F. Wright,Margaret J. Wright,Qiong Yang,Qiong Yang,Hélène Amieva,John Attia,David A. Bennett,Henry Brodaty,A.J.M. de Craen,Caroline Hayward,M. A. Ikram,Ulman Lindenberger,Lars-Göran Nilsson,David J. Porteous,Katri Räikkönen,Ivar Reinvang,Igor Rudan,Perminder S. Sachdev,Reinhold Schmidt,Peter R. Schofield,Peter R. Schofield,Velandai Srikanth,Velandai Srikanth,John M. Starr,Stephen T. Turner,David R. Weir,James F. Wilson,C M van Duijn,L. J. Launer,Annette L. Fitzpatrick,Sudha Seshadri,Sudha Seshadri,Thomas H. Mosley,Ian J. Deary +151 more
TL;DR: In hypothesis-driven tests, there was significant association between general cognitive function and four genes previously associated with Alzheimer’s disease: TOMM40, APOE, ABCG1 and MEF2C.
Journal ArticleDOI
Alzheimer's disease after remote head injury: an incidence study.
Peter W. Schofield,Ming Xin Tang,Karen Marder,Karen L. Bell,George Dooneief,M Chun,Mary Sano,Yaakov Stern,Richard Mayeux +8 more
TL;DR: Cox proportional hazards modelling showed that a history of head injury with loss of consiousness reported to the physician was associated with earlier onset of dementia due to Alzheimer's disease, consistent with the findings of several case-control studies suggesting that head injury may be a risk factor for Alzheimer's Disease.
Journal ArticleDOI
Association of subjective memory complaints with subsequent cognitive decline in community-dwelling elderly individuals with baseline cognitive impairment
TL;DR: Memory complaints may lack validity in subjects with normal cognition, but in nondemented individuals with cognitive impairment, memory complaints may predict subsequent cognitive decline.