K
Kaoru Ito
Researcher at Harvard University
Publications - 30
Citations - 1763
Kaoru Ito is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 11, co-authored 14 publications receiving 1146 citations. Previous affiliations of Kaoru Ito include Massachusetts Institute of Technology.
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Journal ArticleDOI
Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation
Carolina Roselli,Mark Chaffin,Lu-Chen Weng,Lu-Chen Weng,Stefanie Aeschbacher,Gustav Ahlberg,Christine M. Albert,Peter Almgren,Alvaro Alonso,Christopher D. Anderson,Christopher D. Anderson,Krishna G. Aragam,Krishna G. Aragam,Dan E. Arking,John Barnard,Traci M. Bartz,Emelia J. Benjamin,Emelia J. Benjamin,Nathan A. Bihlmeyer,Joshua C. Bis,Heather L. Bloom,Eric Boerwinkle,Erwin B. Bottinger,Jennifer A. Brody,Hugh Calkins,Archie Campbell,Thomas P. Cappola,John F. Carlquist,John F. Carlquist,Daniel I. Chasman,Daniel I. Chasman,Lin Y. Chen,Yii-Der Ida Chen,Eue Keun Choi,Seung Hoan Choi,Ingrid E. Christophersen,Ingrid E. Christophersen,Ingrid E. Christophersen,Mina K. Chung,John W. Cole,John W. Cole,David Conen,David Conen,James P. Cook,Harry J.G.M. Crijns,Michael J. Cutler,Scott M. Damrauer,Scott M. Damrauer,Brian R. Daniels,Dawood Darbar,Graciela Delgado,Joshua C. Denny,Martin Dichgans,Martin Dichgans,Marcus Dörr,Elton A. M. P. Dudink,Samuel C. Dudley,Nada Esa,Tõnu Esko,Tõnu Esko,Markku Eskola,Diane Fatkin,Diane Fatkin,Diane Fatkin,Stephan B. Felix,Ian Ford,Oscar H. Franco,Bastiaan Geelhoed,Raji P. Grewal,Raji P. Grewal,Vilmundur Gudnason,Xiuqing Guo,Namrata Gupta,Stefan Gustafsson,Rebecca Gutmann,Anders Hamsten,Tamara B. Harris,Caroline Hayward,Susan R. Heckbert,Susan R. Heckbert,Jussi Hernesniemi,Lynne J. Hocking,Albert Hofman,Andrea R. V. R. Horimoto,Jie Huang,Paul L. Huang,Jennifer E. Huffman,Erik Ingelsson,Erik Ingelsson,Esra Gucuk Ipek,Kaoru Ito,Jordi Jimenez-Conde,Jordi Jimenez-Conde,Renee Johnson,J. Wouter Jukema,Stefan Kääb,Mika Kähönen,Yoichiro Kamatani,John P. Kane,Adnan Kastrati,Sekar Kathiresan,Sekar Kathiresan,Petra Katschnig-Winter,Maryam Kavousi,Thorsten Kessler,Bas L.J.H. Kietselaer,Paulus Kirchhof,Marcus E. Kleber,Stacey Knight,Stacey Knight,José Eduardo Krieger,Michiaki Kubo,Lenore J. Launer,Jari Laurikka,Terho Lehtimäki,Kirsten Leineweber,Rozenn N. Lemaitre,Man Li,Man Li,Hong Euy Lim,Henry J. Lin,Honghuang Lin,Honghuang Lin,Lars Lind,Cecilia M. Lindgren,Marja-Liisa Lokki,Barry London,Ruth J. F. Loos,Siew-Kee Low,Yingchang Lu,Leo-Pekka Lyytikäinen,Peter W. Macfarlane,Patrik K. E. Magnusson,Anubha Mahajan,Rainer Malik,Alfredo José Mansur,Gregory M. Marcus,Lauren Margolin,Kenneth B. Margulies,Winfried März,Winfried März,David D. McManus,Olle Melander,Sanghamitra Mohanty,Jay A. Montgomery,Michael Morley,Andrew P. Morris,Martina Müller-Nurasyid,Andrea Natale,Saman Nazarian,Benjamin Neumann,Christopher Newton-Cheh,Christopher Newton-Cheh,Maartje N. Niemeijer,Kjell Nikus,Peter M. Nilsson,Raymond Noordam,Heidi Oellers,Morten S. Olesen,Marju Orho-Melander,Sandosh Padmanabhan,Hui Nam Pak,Guillaume Paré,Guillaume Paré,Nancy L. Pedersen,Joanna Pera,Alexandre C. Pereira,David J. Porteous,Bruce M. Psaty,Bruce M. Psaty,Sara L. Pulit,Sara L. Pulit,Sara L. Pulit,Clive R. Pullinger,Daniel J. Rader,Lena Refsgaard,Marta Ribasés,Marta Ribasés,Paul M. Ridker,Michiel Rienstra,Lorenz Risch,Dan M. Roden,Jonathan Rosand,Jonathan Rosand,Michael A. Rosenberg,Michael A. Rosenberg,Natalia S. Rost,Natalia S. Rost,Jerome I. Rotter,Samir Saba,Roopinder K. Sandhu,Renate B. Schnabel,Katharina Schramm,Heribert Schunkert,Claudia Schurman,Stuart A. Scott,Ilkka Seppälä,Christian M. Shaffer,Svati H. Shah,Alaa Shalaby,Alaa Shalaby,Jaemin Shim,M. Benjamin Shoemaker,Joylene E. Siland,Juha Sinisalo,Moritz F. Sinner,Agnieszka Slowik,Albert V. Smith,Blair H. Smith,J. Gustav Smith,J. Gustav Smith,Jonathan D. Smith,Nicholas L. Smith,Nicholas L. Smith,Elsayed Z. Soliman,Nona Sotoodehnia,Bruno H. Stricker,Albert Y. Sun,Han Sun,Jesper Hastrup Svendsen,Toshihiro Tanaka,Kahraman Tanriverdi,Kent D. Taylor,Maris Teder-Laving,Alexander Teumer,Sébastien Thériault,Sébastien Thériault,Stella Trompet,Nathan R. Tucker,Nathan R. Tucker,Arnljot Tveit,Arnljot Tveit,André G. Uitterlinden,Pim van der Harst,Isabelle C. Van Gelder,David R. Van Wagoner,Niek Verweij,Efthymia Vlachopoulou,Uwe Völker,Biqi Wang,Peter Weeke,Peter Weeke,Bob Weijs,Raul Weiss,Stefan Weiss,Quinn S. Wells,Kerri L. Wiggins,Jorge A. Wong,Daniel Woo,Bradford B. Worrall,Pil Sung Yang,Jie Yao,Zachary T. Yoneda,Tanja Zeller,Lingyao Zeng,Steven A. Lubitz,Steven A. Lubitz,Kathryn L. Lunetta,Kathryn L. Lunetta,Patrick T. Ellinor,Patrick T. Ellinor +260 more
TL;DR: This large, multi-ethnic genome-wide association study identifies 97 loci significantly associated with atrial fibrillation that are enriched for genes involved in cardiac development, electrophysiology, structure and contractile function.
Journal ArticleDOI
Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data
Joseph T. Glessner,Alexander G. Bick,Kaoru Ito,Jason Homsy,Laura Rodriguez-Murillo,Menachem Fromer,Erica Mazaika,Badri N. Vardarajan,Michael J. Italia,Jeremy Leipzig,Steven R. DePalma,Ryan Golhar,Stephen Sanders,Boris Yamrom,Michael Ronemus,Ivan Iossifov,A. Jeremy Willsey,Matthew W. State,Jonathan R. Kaltman,Peter White,Yufeng Shen,Dorothy Warburton,Martina Brueckner,Christine E. Seidman,Elizabeth Goldmuntz,Bruce D. Gelb,Richard P. Lifton,Jonathan G. Seidman,Hakon Hakonarson,Wendy K. Chung +29 more
TL;DR: In this paper, the contribution of de novo copy number variants (CNVs) in the pathogenesis of sporadic Congenital Heart Disease (CHD) was investigated using genome-wide dense single nucleotide polymorphism arrays and whole exome sequencing.
Journal ArticleDOI
Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.
Pablo García-Pavía,Yuri Kim,Maria Alejandra Restrepo-Cordoba,Ida G. Lunde,Ida G. Lunde,Hiroko Wakimoto,Amanda M. Smith,Christopher N. Toepfer,Christopher N. Toepfer,Kelly D. Getz,Joshua M. Gorham,Parth N Patel,Parth N Patel,Kaoru Ito,Jonathan A. Willcox,Zoltan Arany,Jian Li,Anjali T. Owens,Risha Govind,Beatriz Nuñez,Erica Mazaika,Antoni Bayes-Genis,Roddy Walsh,Brian S. Finkelman,Josep Lupón,Nicola Whiffin,Nicola Whiffin,Isabel Serrano,William Midwinter,Alicja Wilk,Alfredo Bardají,Nathan Ingold,Rachel Buchan,Upasana Tayal,Domingo A. Pascual-Figal,Antonio de Marvao,Antonio de Marvao,Mian Ahmad,José Manuel García-Pinilla,Antonis Pantazis,Fernando Domínguez,A. John Baksi,Declan P. O'Regan,Stuart D. Rosen,Sanjay K Prasad,Enrique Lara-Pezzi,Enrique Lara-Pezzi,Mariano Provencio,Alexander R. Lyon,Luis Alonso-Pulpón,Stuart A. Cook,Stuart A. Cook,Stuart A. Cook,Steven R. DePalma,Steven R. DePalma,Paul J.R. Barton,Richard Aplenc,Jonathan G. Seidman,Bonnie Ky,James S. Ware,James S. Ware,Christine E. Seidman +61 more
TL;DR: This research presents a novel probabilistic approach that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus as a source of infection for other animals.
Journal ArticleDOI
Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans.
Rakhi P. Naik,Vimal K. Derebail,Morgan E. Grams,Nora Franceschini,Paul L. Auer,Gina M. Peloso,Bessie A. Young,Guillaume Lettre,Carmen A. Peralta,Ronit Katz,Hyacinth I. Hyacinth,Rakale C. Quarells,Megan L. Grove,Alexander G. Bick,Pierre Fontanillas,Stephen S. Rich,Joshua D. Smith,Eric Boerwinkle,Wayne D. Rosamond,Kaoru Ito,Sophie Lanzkron,Josef Coresh,Adolfo Correa,Gloria E. Sarto,Nigel S. Key,David R. Jacobs,Sekar Kathiresan,Kirsten Bibbins-Domingo,Abhijit V. Kshirsagar,James G. Wilson,Alexander P. Reiner +30 more
TL;DR: The findings suggest that SCT may be associated with the higher risk of kidney disease in African Americans, compared with noncarriers.
Journal ArticleDOI
Increased Burden of Cardiovascular Disease in Carriers of APOL1 Genetic Variants
Kaoru Ito,Alexander G. Bick,Jason Flannick,David J. Friedman,Giulio Genovese,Michael Parfenov,Steven R. DePalma,Namrata Gupta,Stacey Gabriel,Herman A. Taylor,Ervin R. Fox,Christopher Newton-Cheh,Sekar Kathiresan,Joel N. Hirschhorn,David Altshuler,Martin R. Pollak,James G. Wilson,Jonathan G. Seidman,Christine E. Seidman +18 more
TL;DR: The increased risk for CVD conferred by APOL1 alleles was robust to correction for both traditional CVD risk factors and chronic kidney disease, indicating a genetic component to cardiovascular health disparities in individuals of African ancestry.