R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
Papers
More filters
Journal ArticleDOI
The use of high-dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome.
Roberto Romero,Jimmy Espinoza,Jimmy Espinoza,Francesca Gotsch,Juan Pedro Kusanovic,Lara A. Friel,Offer Erez,Shali Mazaki-Tovi,Nandor Gabor Than,Sonia S. Hassan,Sonia S. Hassan,Gerard Tromp +11 more
TL;DR: Data is reviewed to examine predisposing factors for preterm birth, transcriptomics to determine changes in mRNA in reproductive tissues associated with preterm labour and preterm prelabour rupture of membranes, and proteomics to identify differentially expressed proteins in amniotic fluid of women with pre term labour.
Journal ArticleDOI
Phenotypic and metabolic characteristics of monocytes and granulocytes in preeclampsia
Maria-Teresa Gervasi,Tinnakorn Chaiworapongsa,Percy Pacora,Nihal Naccasha,Bo Hyun Yoon,Eli Maymon,Roberto Romero +6 more
TL;DR: Preeclampsia is associated with phenotypic and metabolic changes in granulocytes and monocytes, and was associated with a significant increase in mean channel brightness for CD11b on granulocyte and monocyte but lower mean channel Brightness for CD62L ongranulocytes than those from women with normal pregnancy.
Journal ArticleDOI
Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics.
Kevin R. Theis,Kevin R. Theis,Roberto Romero,Andrew D. Winters,Jonathan M. Greenberg,Nardhy Gomez-Lopez,Ali Alhousseini,Ali Alhousseini,Janine Bieda,Janine Bieda,Eli Maymon,Eli Maymon,Eli Maymon,Percy Pacora,Percy Pacora,Jennifer M. Fettweis,Gregory A. Buck,Kimberly K. Jefferson,Jerome F. Strauss,Offer Erez,Offer Erez,Offer Erez,Sonia S. Hassan +22 more
TL;DR: Whether the human placenta delivered at term in patients without labor who undergo cesarean delivery harbors a resident microbiota, which is the assemblage of microorganisms present in a defined niche or environment, is determined.
Journal ArticleDOI
A sonographic short cervix as the only clinical manifestation of intra-amniotic infection.
Sonia S. Hassan,Roberto Romero,Israel Hendler,Ricardo Gomez,Nahla Khalek,Jimmy Espinoza,Jyh Kae Nien,Stanley M. Berry,Emmanuel Bujold,Natalia Camacho,Yoram Sorokin +10 more
TL;DR: Sub-clinical MIAC was detected in 9% of patients with a sonographically short cervix and maternal parenteral treatment with antibiotics can eradicate MIAC caused by Ureaplasma urealyticum, and this was associated with delivery at term in three patients whose successful treatment was documented by microbiologic studies.
Journal ArticleDOI
Phenotypic and metabolic characteristics of monocytes and granulocytes in normal pregnancy and maternal infection
Nihal Naccasha,Maria-Teresa Gervasi,Tinnakorn Chaiworapongsa,Susan Berman,Bo Hyun Yoon,Eli Maymon,Roberto Romero +6 more
TL;DR: Qualitative differences indicate that the innate limb of the immune response is not maximally activated during normal pregnancy, and pregnant women with acute infection had more marked phenotypic and metabolic changes of leukocytes than normal pregnant women.