R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
Infection and labor. III. Interleukin‐1: A signal for the onset of parturition
Roberto Romero,Dan T. Brody,E. Oyarzun,Moshe Mazor,Ying King Wu,John C. Hobbins,Scott K. Durum +6 more
TL;DR: The hypothesis that interleukin-1 may play a role in the initiation of preterm labor associated with intraamniotic infection is supported.
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Myometrial Transcriptional Signatures of Human Parturition.
Zachary Stanfield,Pei F. Lai,Kaiyu Lei,Mark R. Johnson,Andrew M. Blanks,Roberto Romero,Mark R. Chance,Sam Mesiano,Mehmet Koyutürk +8 more
TL;DR: Three transcriptome datasets were integrated, one novel, one existing and two existing, to characterize the gene expression changes in myometrium associated with the onset of labor at term and provide new genes/signaling interactions to understand phenotype-specific processes and aid in future studies of parturition.
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Full-length human placental sFlt-1-e15a isoform induces distinct maternal phenotypes of preeclampsia in mice.
Gabor Szalai,Roberto Romero,Tinnakorn Chaiworapongsa,Yi Xu,Bing Wang,Hyunyoung Ahn,Zhonghui Xu,Po Jen Chiang,Birgitta Sundell,Rona Wang,Yang Jiang,Olesya Plazyo,Mary Olive,Adi L. Tarca,Zhong Dong,Faisal Qureshi,Zoltán Papp,Sonia S. Hassan,Sonia S. Hassan,Edgar Hernandez-Andrade,Edgar Hernandez-Andrade,Nandor Gabor Than +21 more
TL;DR: It is found that hsFlt-1-e15a is central to the terminal pathway of preeclampsia, and it can induce the full spectrum of symptoms in this obstetrical syndrome.
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Adiponectin in amniotic fluid in normal pregnancy, spontaneous labor at term, and preterm labor: A novel association with intra-amniotic infection/inflammation
Shali Mazaki-Tovi,Roberto Romero,Edi Vaisbuch,Juan Pedro Kusanovic,Offer Erez,Pooja Mittal,Francesca Gotsch,Tinnakorn Chaiworapongsa,Nandor Gabor Than,Sun Kwon Kim,Percy Pacora,Lami Yeo,Zhong Dong,Sonia S. Hassan +13 more
TL;DR: It is suggested that adiponectin plays a dynamic role in normal gestation and in the presence of IAI, which is a physiologic constituent of AF.
Journal ArticleDOI
High tissue factor activity and low tissue factor pathway inhibitor concentrations in patients with preterm labor
Offer Erez,Roberto Romero,Edi Vaisbuch,Juan Pedro Kusanovic,Shali Mazaki-Tovi,Tinnakorn Chaiworapongsa,Francesca Gotsch,Jawed Fareed,Debra Hoppensteadt,Nandor Gabor Than,Bo Hyun Yoon,Sam Edwin,Zhong Dong,Jimmy Espinoza,Moshe Mazor,Sonia S. Hassan +15 more
TL;DR: Women with preterm parturition, in contrast to those in labor at term, have a higher TF activity and a lower TFPI concentration, without a significant change in the median maternal plasma TF concentration.