R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
Papers
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The "Great Obstetrical Syndromes" are associated with disorders of deep placentation.
TL;DR: Criteria for the classification of defective deep placentation into 3 types is proposed based on the degree of restriction of remodeling and the presence of obstructive lesions in the myometrial segment of the spiral arteries.
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A systems biology approach for pathway level analysis
Sorin Draghici,Purvesh Khatri,Adi L. Tarca,Kashyap Amin,Arina Done,Calin Voichita,Constantin Georgescu,Roberto Romero +7 more
TL;DR: An impact analysis is developed that includes the classical statistics but also considers other crucial factors such as the magnitude of each gene's expression change, their type and position in the given pathways, their interactions, etc.
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The fetal inflammatory response syndrome.
TL;DR: The fetal systemic inflammatory response as a mechanism of disease is reviewed and potential interventions to control an exaggerated inflammatory response in utero are also described.
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A novel signaling pathway impact analysis
Adi L. Tarca,Sorin Draghici,Purvesh Khatri,Sonia S. Hassan,Pooja Mittal,Jung-Sun Kim,Chong Jai Kim,Juan Pedro Kusanovic,Roberto Romero +8 more
TL;DR: A novel signaling pathway impact analysis (SPIA) that combines the evidence obtained from the classical enrichment analysis with a novel type of evidence, which measures the actual perturbation on a given pathway under a given condition.
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A review of premature birth and subclinical infection
TL;DR: Results support the hypothesis that premature birth results in part from infection caused by genital tract bacteria, and research efforts must be prioritized to determine the role of infection and the appropriate prevention of this cause of prematurity.