R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Toll-like receptor 4: A potential link between “danger signals,” the innate immune system, and preeclampsia?
Yeon Mee Kim,Roberto Romero,Seo Young Oh,Chong Jai Kim,Brian A. Kilburn,D. Randall Armant,Jyh Kae Nien,Ricardo Gomez,Moshe Mazor,Shigeru Saito,Vikki M. Abrahams,Gil Mor +11 more
TL;DR: It is proposed that "danger signals" at the feto-maternal interface, which are recognized by trophoblasts through TLR-4, may play a key role in the creation of a local abnormal cytokine milieu.
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Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance.
Roberto Romero,Jezid Miranda,Tinnakorn Chaiworapongsa,Piya Chaemsaithong,Francesca Gotsch,Zhong Dong,Ahmed I. Ahmed,Bo Hyun Yoon,Sonia S. Hassan,Chong J. Kim,Steven J. Korzeniewski,Lami Yeo,Yeon Mee Kim +12 more
TL;DR: Sterile intra-amniotic inflammation is more common than microbial-associated intra-ammiotic inflammation in asymptomatic women with a sonographic short cervix, and is associated with increased risk of sPTD (<34 weeks).
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Elevated interleukin-8 concentrations in amniotic fluid of mothers whose neonates subsequently develop bronchopulmonary dysplasia.
Fabio Ghezzi,Ricardo Gomez,Roberto Romero,Bo Hyun Yoon,Samuel S. Edwin,C. David,James Janisse,Moshe Mazor +7 more
TL;DR: It is proposed that in utero aspiration of fluid with high concentration of pro-inflammatory mediators may contribute to the lung injury responsible for the development of bronchopulmonary dysplasia.
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Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity.
Roberto Romero,Offer Erez,Offer Erez,Offer Erez,Maik Hüttemann,Eli Maymon,Eli Maymon,Eli Maymon,Bogdan Panaitescu,Agustin Conde-Agudelo,Percy Pacora,Percy Pacora,Bo Hyun Yoon,Lawrence I. Grossman +13 more
TL;DR: The mechanisms by which metformin may prevent preeclampsia include a reduction in the production of antiangiogenic factors and the improvement of endothelial dysfunction, probably through an effect on the mitochondria.
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Treatment of abnormal vaginal flora in early pregnancy with clindamycin for the prevention of spontaneous preterm birth: A systematic review and metaanalysis
Ronald F. Lamont,Chia Ling Nhan-Chang,Chia Ling Nhan-Chang,Jack D. Sobel,Kimberly A. Workowski,Kimberly A. Workowski,Agustin Conde-Agudelo,Roberto Romero +7 more
TL;DR: There is evidence to justify further randomized controlled trials of clindamycin for the prevention of preterm birth and a deeper understanding of the vaginal microbiome, mucosal immunity, and the biology of BV will be needed to inform the design of such trials.