Roberto Romero

TL;DR: Findings provide in vivo evidence that there is inflammasome activation in the amniotic cavity during the physiological process of labor at term, and suggest that these cells are a source of extracellular ASC in theAmniotic fluid.

TL;DR: The pregnancy outcomes of patients with midtrimester cervical insufficiency and bulging membranes are poor as they have a high prevalence of intra-amniotic infection/inflammation, and a pre-operative amniocentesis is key to identify the best candidates for the subsequent placement of a cerclage.

TL;DR: A distinctive fetal growth pattern across gestation preceding spontaneous late preterm birth is documented, for the first time, to identify the importance of mid‐gestation for alterations in fetal growth, and add perspective on human fetal biological variability.

TL;DR: It is found that the serum PSG1 concentration is lower in African-American women diagnosed with early-onset and late-ONSet preeclampsia, a pregnancy pathology characterized by shallow trophoblast invasion, than in their respective healthy controls only when the fetus was a male; therefore, the reduced expression of this molecule should be considered in the context of preeClampsia as a potential therapy.

TL;DR: Findings support the view of a link between angiopoietins and inflammation and the median Ang-2 concentration in amniotic fluid is higher in patients with IAI than in those without; and spontaneous parturition at term is not associated with changes in the AF concentration of Ang- 2.