R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Evidence to support that spontaneous preterm labor is adaptive in nature: neonatal RDS is more common in "indicated" than in "spontaneous" preterm birth
TL;DR: The view that spontaneous preterm labor is adaptive in nature is supported, as there is a difference in the frequency of neonatal respiratory distress syndrome according to the etiology of preterm birth.
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Maternal plasma concentrations of the soluble tumor necrosis factor receptor 2 are increased prior to the diagnosis of preeclampsia
Baha M. Sibai,Baha M. Sibai,Roberto Romero,Mark A. Klebanoff,Madeline Murguia Rice,Steve N. Caritis,Marshall D. Lindheimer,J. Peter Van Dorsten,Mark B. Landon,Menachem Miodovnik,Mitchell P. Dombrowski,Paul J. Meis +11 more
TL;DR: Soluble receptor levels of tumor necrosis factor (sTNF-R)-1 and -2 are increased during preeclampsia, suggesting a pathogenetic role for these proinflammatory cytokines.
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Maternal serum soluble CD30 is increased in normal pregnancy, but decreased in preeclampsia and small for gestational age pregnancies
Juan Pedro Kusanovic,Roberto Romero,Sonia S. Hassan,Francesca Gotsch,Samuel Edwin,Tinnakorn Chaiworapongsa,Offer Erez,Pooja Mittal,Shali Mazaki-Tovi,Eleazar Soto,Nandor Gabor Than,Lara A. Friel,Bo Hyun Yoon,Jimmy Espinoza +13 more
TL;DR: This finding is consistent with the view that preeclampsia and SGA are associated with a polarized Th1 immune response and, perhaps, a reduced Th2 response.
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Endothelin-1,2 levels are increased in the amniotic fluid of women with preterm labor and microbial invasion of the amniotic cavity
TL;DR: A role for endothelins in the mechanisms responsible for preterm delivery associated with intraamniotic infection is supported, and women with preterm labor and positive amniotic fluid cultures for microorganisms had higher amniotics fluid concentrations of endothelin-1,2.
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Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors.
Wendy Fitzgerald,Nardhy Gomez-Lopez,Nardhy Gomez-Lopez,Offer Erez,Offer Erez,Offer Erez,Roberto Romero,Leonid Margolis +7 more
TL;DR: This work developed an ex vivo system that retains placental cytoarchitecture and the primary metabolic aspects and investigated the pattern of secretion of cytokines, growth factors, and extracellular vesicles by placental villous and amnion tissues ex vivo.