R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
Isolation of Ureaplasma urealyticum from the amniotic cavity and adverse outcome in preterm labor
TL;DR: Microbial invasion of the amniotic cavity with U urealyticum is a risk factor for impending preterm delivery and adverse perinatal outcome in women with preterm labor.
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Universal Cervical Length Screening and Treatment with Vaginal Progesterone to Prevent Preterm Birth: A Decision and Economic Analysis
Alison G. Cahill,Anthony Odibo,Aaron B. Caughey,David Stamilio,Sonia S. Hassan,Sonia S. Hassan,George A. Macones,Roberto Romero,Roberto Romero +8 more
TL;DR: Universal sonographic screening for short cervical length and treatment with vaginal progesterone appears to be cost-effective and yields the greatest reduction in preterm birth at <34 weeks' gestation.
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TLR9 Activation Coupled to IL-10 Deficiency Induces Adverse Pregnancy Outcomes
TL;DR: Pregnancy complications in IL-10−/− mice were associated with unexpected and robust TLR9-triggered activation and amplification of uterine neutrophil and macrophage subpopulations followed by their migration to the placental zone and have important implications for IL- 10-mediated “uterine tolerance” against CpG-driven innate immune activation.
Journal ArticleDOI
Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection.
Eli Maymon,Roberto Romero,Percy Pacora,Maria-Teresa Gervasi,R. Gomez,Samuel S. Edwin,Bo Hyun Yoon +6 more
TL;DR: The authors' observations provide evidence for a novel regulation of gelatinolytic activity in vivo and explore the participation of these enzymes in labor, rupture of membranes, and microbial invasion of the amniotic cavity.
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Maternal serum interleukin-6, C-reactive protein, and matrix metalloproteinase-9 concentrations as risk factors for preterm birth <32 weeks and adverse neonatal outcomes.
Yoram Sorokin,Roberto Romero,Lisa Mele,Ronald J. Wapner,Ronald J. Wapner,Jay D. Iams,Jay D. Iams,Donald J. Dudley,Donald J. Dudley,Catherine Y. Spong,Alan M. Peaceman,Alan M. Peaceman,Kenneth J. Leveno,Kenneth J. Leveno,Margaret Harper,Margaret Harper,Steve N. Caritis,Steve N. Caritis,Menachem Miodovnik,Menachem Miodovnik,Menachem Miodovnik,Brian M. Mercer,Brian M. Mercer,John M. Thorp,John M. Thorp,Mary Jo O'Sullivan,Mary Jo O'Sullivan,Susan M. Ramin,Susan M. Ramin,Marshall W. Carpenter,Marshall W. Carpenter,D.J. Rouse,D.J. Rouse,Baha Sibai,Baha Sibai +34 more
TL;DR: High maternal serum concentrations of IL-6 and CRP, but not MMP-9, were associated with an increased risk of IVH, and neonatal sepsis was more frequent in neonates born to mothers with a high maternal serum concentration of CRP.