R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
Transport and biodistribution of dendrimers across human fetal membranes: implications for intravaginal administration of dendrimer-drug conjugates.
Anupa R. Menjoge,Raghavendra S. Navath,Raghavendra S. Navath,Abbas Asad,Sujatha Kannan,Chong Jai Kim,Roberto Romero,Rangaramanujam M. Kannan,Rangaramanujam M. Kannan +8 more
TL;DR: The overall findings suggest that entry of drugs conjugated to dendrimers would be restricted across the human fetal membranes when administered topically by intravaginal route, suggesting new ways of selectively delivering therapeutics to the mother without affecting the fetus.
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Epithelial Cell-Derived Neutrophil-Activating Peptide-78 Is Present in Fetal Membranes and Amniotic Fluid at Increased Concentrations with Intra-amniotic Infection and Preterm Delivery
Jeffrey A. Keelan,Joseph Yuan-Mou Yang,Roberto Romero,Tinnakorn Chaiworapongsa,K.W. Marvin,Timothy A. Sato,Murray D. Mitchell +6 more
TL;DR: It is concluded that ENA-78, derived from the gestational membranes, is present in increased abundance in the amniotic cavity in response to intrauterine infection and, hence, may play a role in the mechanism of infection-driven preterm birth and rupture of membranes secondary to leukocyte recruitment and activation.
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Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes
Nardhy Gomez-Lopez,Nardhy Gomez-Lopez,Marcia Arenas-Hernandez,Marcia Arenas-Hernandez,Marcia Arenas-Hernandez,Roberto Romero,Derek Miller,Derek Miller,Valeria Garcia-Flores,Valeria Garcia-Flores,Yaozhu Leng,Yaozhu Leng,Yi Xu,Yi Xu,Jose Galaz,Jose Galaz,Sonia S. Hassan,Sonia S. Hassan,Chaur-Dong Hsu,Chaur-Dong Hsu,Harley Y. Tse,Carmen Sánchez-Torres,Bogdan Done,Bogdan Done,Adi L. Tarca,Adi L. Tarca,Adi L. Tarca +26 more
TL;DR: It is reported that functional Tregs are reduced at the maternal-fetal interface in a subset of women with idiopathic preterm labor/birth, which is accompanied by a concomitant increase in Tc17 cells.
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Four-dimensional ultrasonography of the fetal heart using a novel Tomographic Ultrasound Imaging display
Luís F. Gonçalves,Jimmy Espinoza,Jimmy Espinoza,Roberto Romero,Roberto Romero,Juan Pedro Kusanovic,Juan Pedro Kusanovic,Betsy Swope,Betsy Swope,Jyh Kae Nien,Offer Erez,Offer Erez,Eleazar Soto,Eleazar Soto,Marjorie C. Treadwell +14 more
TL;DR: Standard transverse planes commonly used to examine the fetal heart can be automatically displayed with TUI in the majority of fetuses undergoing 4D US with STIC, and the sensitivity, specificity, positive- and negative-predictive values of TUI to diagnose congenital heart disease are found.
Journal ArticleDOI
The calcium binding protein, S100B, is increased in the amniotic fluid of women with intra-amniotic infection/inflammation and preterm labor with intact or ruptured membranes.
Lara A. Friel,Roberto Romero,Roberto Romero,Sam Edwin,Jyh Kae Nien,Ricardo Gomez,Tinnakorn Chaiworapongsa,Juan Pedro Kusanovic,Jorge E. Tolosa,Jorge E. Tolosa,Sonia S. Hassan,Jimmy Espinoza +11 more
TL;DR: An elevated concentration of AF S100B may reflect intra-amniotic infection/inflammation and not necessarily fetal neurologic damage.