R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
Papers
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Journal ArticleDOI
Evolution of non-cytotoxic uterine natural killer cells.
Satyan Kalkunte,Clinton O. Chichester,Francesca Gotsch,Charles L. Sentman,Roberto Romero,Surendra Sharma +5 more
TL;DR: In this paper, the authors propose that the endometrium/decidua functions as an "inducible tertiary lymphoid tissue" that supports the recruitment and expansion of CD56(bright)CD16(-) NK cells and induces transcriptional up-regulation of angiogenic machinery in response to exposure to local hormonal factors, cytokine milieu and perhaps hypoxia.
Journal ArticleDOI
Human beta-defensin-2: a natural antimicrobial peptide present in amniotic fluid participates in the host response to microbial invasion of the amniotic cavity.
Eleazar Soto,Jimmy Espinoza,Jyh Kae Nien,Juan Pedro Kusanovic,Offer Erez,Karina Richani,Joaquin Santolaya-Forgas,Roberto Romero +7 more
TL;DR: It is proposed that amniotic fluid HBD-2 is part of the innate immune system within theAmniotic cavity, and this may account for some of the antimicrobial activity of amniotics fluid.
Journal ArticleDOI
A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans
Hongyan Wang,Samuel Parry,George A. Macones,Mary D. Sammel,Helena Kuivaniemi,Gerard Tromp,George Argyropoulos,Indrani Halder,Mark D. Shriver,Roberto Romero,Jerome F. Strauss,Jerome F. Strauss +11 more
TL;DR: This article investigated the contribution of a functional SNP in the promoter of the SERPINH1 gene, enriched among those of African ancestry, to preterm premature rupture of membranes (PPROM), the leading identifiable cause of preterm birth.
Journal ArticleDOI
Preeclampsia: a link between trophoblast dysregulation and an antiangiogenic state
TL;DR: A 24-year-old nulliparous woman developed mildly elevated blood pressure without proteinuria at 30⁶/⁷ weeks of gestation and was diagnosed with severe preeclampsia/HELLP syndrome, and antenatal steroids were administered to induce fetal lung maturity.
Book ChapterDOI
Interleukin 6 Determination in the Detection of Microbial Invasion of the Amniotic Cavity
Roberto Romero,Waldo Sepulveda,John S. Kenney,Linda E. Archer,Anthony C. Allison,Pravinkumar B. Sehgal +5 more
TL;DR: Whether measurement of amniotic fluid concentrations of interleukin 6 could be of value in the diagnosis of microbial invasion of theAmniotic cavity was established and patients with an amniotics fluid interleucin 6 level above 11.2 ng/ml were at risk for congenital infections.