R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsia.
Nandor Gabor Than,Roberto Romero,Yi Xu,Offer Erez,Zhonghui Xu,Gaurav Bhatti,Ron Leavitt,Tzu Hung Chung,Haidy El-Azzamy,Christopher LaJeunesse,Bing Wang,Andrea Balogh,Andrea Balogh,Gabor Szalai,Susan Land,Zhong Dong,Sonia S. Hassan,Sonia S. Hassan,Tinnakorn Chaiworapongsa,Tinnakorn Chaiworapongsa,Manuel Krispin,Chong Jai Kim,Chong Jai Kim,Adi L. Tarca,Adi L. Tarca,Zoltán Papp,Hans Bohn +26 more
TL;DR: The evolutionary origins of the placental expression of Chr19 cluster galectin genes are revealed and the complex dysregulation of these genes in preeclampsia may alter immune tolerance mechanisms at the maternal-fetal interface.
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Resistin: a hormone which induces insulin resistance is increased in normal pregnancy.
Jyh Kae Nien,Shali Mazaki-Tovi,Roberto Romero,Juan Pedro Kusanovic,Offer Erez,Francesca Gotsch,Beth L. Pineles,Lara A. Friel,Jimmy Espinoza,Luís F. Gonçalves,Joaquin Santolaya,Ricardo Gomez,Joon Seok Hong,Samuel S. Edwin,Eleazar Soto,Karina Richani,Moshe Mazor,Sonia S. Hassan +17 more
TL;DR: Normal pregnant women have a higher median plasma concentration of resistin than non-pregnant women and the concentration of this adipokine increases with advancing gestation, which could contribute to metabolic changes of pregnancy.
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Severe preeclampsia is characterized by increased placental expression of galectin-1.
Nandor Gabor Than,Offer Erez,Derek E. Wildman,Adi L. Tarca,Samuel Edwin,Asad Abbas,John W. Hotra,Juan Pedro Kusanovic,Francesca Gotsch,Sonia S. Hassan,Jimmy Espinoza,Zoltán Papp,Roberto Romero +12 more
TL;DR: Placental galectin-1 expression is higher in severe PE than in normal pregnancy regardless of the presence of SGA, and the protein is abundantly present in third trimester human placentas, suggesting it may be implicated in maternal–fetal immune tolerance in humans.
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Familial aggregation of hyperemesis gravidarum
Yafeng Zhang,Rita M. Cantor,Kimber MacGibbon,Roberto Romero,Thomas M. Goodwin,Patrick M. Mullin,Marlena S. Fejzo,Marlena S. Fejzo +7 more
TL;DR: This study provides strong evidence for a genetic component to HG and identification of the predisposing gene(s) may determine the cause of this poorly understood disease of pregnancy.
Journal ArticleDOI
Sex differences in functional connectivity during fetal brain development
Muriah D. Wheelock,Jasmine L. Hect,Edgar Hernandez-Andrade,Sonia S. Hassan,Roberto Romero,Adam T. Eggebrecht,Moriah E. Thomason,Moriah E. Thomason,Moriah E. Thomason +8 more
TL;DR: It is confirmed for the first time that network FC differs with sex in utero, and 16 distinct fetal FC networks were identified using a community detection algorithm.