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Ruth Mitchell

Researcher at University of Bristol

Publications -  27
Citations -  736

Ruth Mitchell is an academic researcher from University of Bristol. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 7 publications receiving 266 citations. Previous affiliations of Ruth Mitchell include Medical Research Council.

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Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

TL;DR: It is found that major health outcomes appear geographically structured and that coincident structure in health outcomes and genotype data can yield biased associations, and that fine-scale structure is detectable in apparently homogeneous samples such as ALSPAC when measured very precisely, and remains detectable in UK Biobank despite conventional approaches to account for it.
Journal ArticleDOI

A saturated map of common genetic variants associated with human height

Loic Yengo, +617 more
- 10 Jan 2022 - 
TL;DR: In this article , the authors show that common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes.
Posted ContentDOI

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications

TL;DR: It is found that single genetic variants are associated with birth location within UK Biobank and that geographic structure in genetic data could not be accounted for using routine adjustment for study centre and principal components derived from genotype data.