Simon Haworth

TL;DR: In both studies, anxiety and depression during the pandemic was greater in younger members, women, those with pre-existing mental/physical health conditions and individuals in socioeconomic adversity, even when controlling for pre-pandemicxiety and depression.

TL;DR: It is found that major health outcomes appear geographically structured and that coincident structure in health outcomes and genotype data can yield biased associations, and that fine-scale structure is detectable in apparently homogeneous samples such as ALSPAC when measured very precisely, and remains detectable in UK Biobank despite conventional approaches to account for it.

TL;DR: It is shown that the heritability of dental caries is enriched for conserved genomic regions and partially overlapping with a range of complex traits including smoking, education, personality traits and metabolic measures, and it is estimated that the processes contributing to dental carie may have undesirable downstream effects on health.

TL;DR: Through a large 25O HD GWAS, 63 loci are identified that underline the contribution of genes outside the vitamin D canonical metabolic pathway to the genetic architecture of 25OHD.

TL;DR: In this article , the authors show that common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes.