Thorgeir E. Thorgeirsson

Researcher at deCODE genetics

Publications - 121

Citations - 22357

Thorgeir E. Thorgeirsson is an academic researcher from deCODE genetics. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 49, co-authored 106 publications receiving 18623 citations. Previous affiliations of Thorgeir E. Thorgeirsson include Lawrence Berkeley National Laboratory & University of California, Santa Cruz.

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Two Modes of Ligand Binding in Maltose-binding Protein ofEscherichia coli: ELECTRON PARAMAGNETIC RESONANCE STUDY OF LIGAND-INDUCED GLOBAL CONFORMATIONAL CHANGES BY SITE-DIRECTED SPIN LABELING

Jason A. Hall, +5 more

- 11 Jul 1997 -

Journal of Biological Chemistry

TL;DR: The present work suggests that the B mode is nonproductive because ligands binding in this manner prevent the closure of the two domains of MBP, and, as a result, the resulting ligand-MBP complex is incapable of interacting properly with the inner membrane-associated transporter complex.

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Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis

Snaevar Sigurdsson, +31 more

- 06 Jun 2017 -

Nature Communications

TL;DR: In the combined Icelandic and Danish data sets, significant association of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15) and FAM155A (family with sequence similarity 155A) are observed, the first loci shown to associate with diverticular disease in a genome-wide study.

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The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.

Wouter J. Peyrot, +324 more

- 26 Jun 2015 -

Molecular Psychiatry

TL;DR: An association of lower EA and MDD risk is confirmed, but this association was not because of measurable pleiotropic genetic effects, which suggests that environmental factors could be involved, for example, socioeconomic status.

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Effects of Asp-96----Asn, Asp-85----Asn, and Arg-82----Gln single-site substitutions on the photocycle of bacteriorhodopsin.

Thorgeir E. Thorgeirsson, +6 more

- 24 Sep 1991 -

Biochemistry

TL;DR: The results suggest that Asp-96 may play a role in regulating the structure of BR and how it changes during the photocycle, but results for D96N suggest a more complex role for AsP-96 than previously suggested.

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Thorgeir E. Thorgeirsson

Papers

Two Modes of Ligand Binding in Maltose-binding Protein ofEscherichia coli: ELECTRON PARAMAGNETIC RESONANCE STUDY OF LIGAND-INDUCED GLOBAL CONFORMATIONAL CHANGES BY SITE-DIRECTED SPIN LABELING

Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.

Effects of Asp-96----Asn, Asp-85----Asn, and Arg-82----Gln single-site substitutions on the photocycle of bacteriorhodopsin.

Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations (vol 156, pg 2337, 2015)