Yu Huang

TL;DR: In situ hybridization and immunohistochemistry revealed that CNGA2 mRNA and proteins were expressed in the endothelium and smooth muscle layers of human coronary and cerebral arteries, suggesting a potential ubiquitous role ofCNGA2 channels in mediating Ca2+ influx in vascular cells.

TL;DR: The results suggest that the combined treatment with PI3K inhibitor BKM120 and PARP inhibitor olaparib may be a promising therapeutic regimen for the treatment of gastric cancer, and ARID1A deficiency could serve as a potential predictive therapeutic biomarker.

TL;DR: In this paper, a thermal elastic-plastic finite element model considering multi-linear yield stress curves and multi-point constraint equations is developed to estimate welding deformation and residual stress, and a simplified heat source model with the actual bead geometry is proposed to reduce the number of finite element meshes.

TL;DR: A new failure dependent design partitioning method is proposed to improve volume diagnosis throughput with a minimal impact on diagnosis quality to increase the throughput of volume diagnosis by increasing the number of failing dies diagnosed within a given time.

TL;DR: Impaired endothelium-dependent renal artery relaxation in ovariectomized rats is mediated largely through increased activity and expression of COX-2 and the thromboxane-prostanoid receptor and restored through downregulating both signaling proteins during estrogen deficiency.