Institution
Institut national de la recherche agronomique
Facility•Rabat, Morocco•
About: Institut national de la recherche agronomique is a facility organization based out in Rabat, Morocco. It is known for research contribution in the topics: Population & Gene. The organization has 41515 authors who have published 68362 publications receiving 3292057 citations. The organization is also known as: INRA & Inra.
Topics: Population, Gene, Soil water, Genome, Quantitative trait locus
Papers published on a yearly basis
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TL;DR: The data suggest that the borate ester is located on C-2 and C-3 of two of the four 3′-linked apiosyl residues of dimeric RG-II, indicating that this plant cell wall pectic polysaccharide is covalently cross-linked.
515 citations
TL;DR: Analysis of culture media extracts showed that some of the inhibitors, particularly vanillin and furaldehyde, could be assimilated by the tested microbial strains which resulted in the partial recovery in both growth and ethanol production processes on prolonged incubation.
514 citations
State University of New York System1, Centre de coopération internationale en recherche agronomique pour le développement2, ENEA3, University of Ottawa4, French Alternative Energies and Atomic Energy Commission5, Bioversity International6, Nestlé7, Bielefeld University8, Institut national de la recherche agronomique9, Chongqing University of Science and Technology10, University of Illinois at Urbana–Champaign11, University of Barcelona12, University of Maryland, College Park13, University of Trieste14, Empresa Brasileira de Pesquisa Agropecuária15, Analytica16, University of Queensland17, Coffee production in India18, University of Arizona19, University of Évry Val d'Essonne20, Centre national de la recherche scientifique21
TL;DR: The Coffea canephora (coffee) genome was sequenced and identified a conserved gene order, and comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem duplications independently of genes from cacao and tea, suggesting that caffeine in eudicots is of polyphyletic origin.
Abstract: Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms. Although it shows no sign of the whole-genome triplication identified in Solanaceae species such as tomato, the genome includes several species-specific gene family expansions, among them N-methyltransferases (NMTs) involved in caffeine production, defense-related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis. Comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem duplications independently of genes from cacao and tea, suggesting that caffeine in eudicots is of polyphyletic origin.
513 citations
TL;DR: Suggestions presented in this paper should help the analyst to design and perform the minimum number validation experiments needed to obtain all the required information to establish and demonstrate the reliability of its analytical procedure.
512 citations
TL;DR: The main obstacles limiting progress are reviewed and recommendations are made to improve the mode of collection and preparation of biological samples, the coverage and quality of mass spectrometry analyses, the extraction and exploitation of the raw data, the identification of the metabolites and the biological interpretation of the results.
Abstract: Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have become methods of choice to characterize the human metabolome and MS-based metabolomics is increasingly used to characterize the complex metabolic effects of nutrients or foods. However progress is still hampered by many unsolved problems and most notably the lack of well established and standardized methods or procedures, and the difficulties still met in the identification of the metabolites influenced by a given nutritional intervention. The purpose of this paper is to review the main obstacles limiting progress and to make recommendations to overcome them. Propositions are made to improve the mode of collection and preparation of biological samples, the coverage and quality of mass spectrometry analyses, the extraction and exploitation of the raw data, the identification of the metabolites and the biological interpretation of the results.
512 citations
Authors
Showing all 41526 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Daniel J. Jacob | 162 | 656 | 76530 |
| Jens J. Holst | 160 | 1536 | 107858 |
| Grant W. Montgomery | 157 | 926 | 108118 |
| Dirk Inzé | 149 | 647 | 74468 |
| Bernard Henrissat | 139 | 593 | 100002 |
| David Julian McClements | 131 | 1137 | 71123 |
| Pascale Cossart | 124 | 434 | 50101 |
| Christine H. Foyer | 116 | 490 | 61381 |
| Eric Verdin | 115 | 370 | 47971 |
| Olivier Hermine | 111 | 1026 | 43779 |
| John Ralph | 109 | 442 | 39238 |
| Edward M. Rubin | 107 | 287 | 62667 |
| Gary Williamson | 106 | 478 | 42960 |
| Stephen L. Hauser | 106 | 561 | 46248 |
| Serge Hercberg | 106 | 942 | 56791 |