National Autonomous University of Mexico

About: National Autonomous University of Mexico is a education organization based out in Mexico City, Distrito Federal, Mexico. It is known for research contribution in the topics: Population & Galaxy. The organization has 72868 authors who have published 127797 publications receiving 2285543 citations. The organization is also known as: UNAM & Universidad Nacional Autónoma de México.

The partitioned Rhizobium etli genome: Genetic and metabolic redundancy in seven interacting replicons

Abstract: We report the complete 6,530,228-bp genome sequence of the symbiotic nitrogen fixing bacterium Rhizobium etli. Six large plasmids comprise one-third of the total genome size. The chromosome encodes most functions necessary for cell growth, whereas few essential genes or complete metabolic pathways are located in plasmids. Chromosomal synteny is disrupted by genes related to insertion sequences, phages, plasmids, and cell-surface components. Plasmids do not show synteny, and their orthologs are mostly shared by accessory replicons of species with multipartite genomes. Some nodulation genes are predicted to be functionally related with chromosomal loci encoding for the external envelope of the bacterium. Several pieces of evidence suggest an exogenous origin for the symbiotic plasmid (p42d) and p42a. Additional putative horizontal gene transfer events might have contributed to expand the adaptive repertoire of R. etli, because they include genes involved in small molecule metabolism, transport, and transcriptional regulation. Twenty-three putative sigma factors, numerous isozymes, and paralogous families attest to the metabolic redundancy and the genomic plasticity necessary to sustain the lifestyle of R. etli in symbiosis and in the soil.

Carbohydrate-binding domains: multiplicity of biological roles

Abstract: Insoluble polysaccharides can be degraded by a set of hydrolytic enzymes formed by catalytic modules appended to one or more non-catalytic carbohydrate-binding modules (CBM). The most recognized function of these auxiliary domains is to bind polysaccharides, bringing the biocatalyst into close and prolonged vicinity with its substrate, allowing carbohydrate hydrolysis. Examples of insoluble polysaccharides recognized by these enzymes include cellulose, chitin, β-glucans, starch, glycogen, inulin, pullulan, and xylan. Based on their amino acid similarity, CBMs are grouped into 55 families that show notable variation in substrate specificity; as a result, their biological functions are miscellaneous. Carbohydrate or polysaccharide recognition by CBMs is an important event for processes related to metabolism, pathogen defense, polysaccharide biosynthesis, virulence, plant development, etc. Understanding of the CBMs properties and mechanisms in ligand binding is of vital significance for the development of new carbohydrate-recognition technologies and provide the basis for fine manipulation of the carbohydrate–CBM interactions.

Irac observations of taurus pre-main-sequence stars

Abstract: We presented infrared photometry obtained with the IRAC camera on the Spitzer Space Telescope of a sample of 82 pre-main-sequence stars and brown dwarfs in the Taurus starforming region. We find a clear separation in some IRAC color-color diagrams between objects with and without disks. A few "transition" objects are noted, which correspond to systems in which the inner disk has been evacuated of small dust. Separating pure disk systems from objects with remnant protostellar envelopes is more difficult at IRAC wavelengths, especially for objects with infall at low rates and large angular momenta. Our results generally confirm the IRAC color classification scheme used in previous papers by Allen et al. and Megeath et al. to distinguish between protostars, T Tauri stars with disks, and young stars without (inner) disks. The observed IRAC colors are in good agreement with recent improved disk models, and in general accord with models for protostellar envelopes derived from analyzing a larger wavelength region. We also comment on a few Taurus objects of special interest. Our results should be useful for interpreting IRAC results in other, less well studied star-forming regions.