Institution
National Autonomous University of Mexico
Education•Mexico City, Distrito Federal, Mexico•
About: National Autonomous University of Mexico is a education organization based out in Mexico City, Distrito Federal, Mexico. It is known for research contribution in the topics: Population & Galaxy. The organization has 72868 authors who have published 127797 publications receiving 2285543 citations. The organization is also known as: UNAM & Universidad Nacional Autónoma de México.
Topics: Population, Galaxy, Catalysis, Thin film, Stars
Papers published on a yearly basis
Papers
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TL;DR: Analysis of stable enhancers identified a new, essential role for a constitutively expressed, lineage-restricted ETS-family transcription factor, EHF, in epidermal differentiation, suggesting that lineage-specific chromatin structure is established in tissue progenitor cells and is further remodeled in terminal differentiation.
Abstract: Chromosome conformation is an important feature of metazoan gene regulation; however, enhancer-promoter contact remodeling during cellular differentiation remains poorly understood. To address this, genome-wide promoter capture Hi-C (CHi-C) was performed during epidermal differentiation. Two classes of enhancer-promoter contacts associated with differentiation-induced genes were identified. The first class ('gained') increased in contact strength during differentiation in concert with enhancer acquisition of the H3K27ac activation mark. The second class ('stable') were pre-established in undifferentiated cells, with enhancers constitutively marked by H3K27ac. The stable class was associated with the canonical conformation regulator cohesin, whereas the gained class was not, implying distinct mechanisms of contact formation and regulation. Analysis of stable enhancers identified a new, essential role for a constitutively expressed, lineage-restricted ETS-family transcription factor, EHF, in epidermal differentiation. Furthermore, neither class of contacts was observed in pluripotent cells, suggesting that lineage-specific chromatin structure is established in tissue progenitor cells and is further remodeled in terminal differentiation.
245 citations
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Alpen-Adria-Universität Klagenfurt1, University of Colorado Boulder2, INSEAD3, National Autonomous University of Mexico4, University of Saskatchewan5, University of California, Santa Barbara6, Finnish Environment Institute7, University of Innsbruck8, Potsdam Institute for Climate Impact Research9, Environment Agency10, University of Copenhagen11, University of Vienna12
TL;DR: Novel concepts to substantially expand long term ecological research by including the human dimension are proposed, changing it from LTER to LTSER, "Long-Term Socioecological Research," with a focus on coupled socioecological systems.
Abstract: Concerns about global environmental change challenge long term ecological research (LTER) to go beyond traditional disciplinary scientific research to produce knowledge that can guide society toward more sustainable development. Reporting the outcomes of a 2 d interdisciplinary workshop, this article proposes novel concepts to substantially expand LTER by including the human dimension. We feel that such an integration warrants the insertion of a new letter in the acronym, changing it from LTER to LTSER, "Long-Term Socioecological Research," with a focus on coupled socioecological systems. We discuss scientific challenges such as the necessity to link biophysical processes to governance and communication, the need to consider patterns and processes across several spatial and temporal scales, and the difficulties of combining data from in-situ measurements with statistical data, cadastral surveys, and soft knowledge from the humanities. We stress the importance of including prefossil fuel system baseline data as well as maintaining the often delicate balance between monitoring and predictive or explanatory modeling. Moreover, it is challenging to organize a continuous process of cross-fertilization between rich descriptive and causal-analytic local case studies and theory/modeling-oriented generalizations. Conceptual insights are used to derive conclusions for the design of infrastructures needed for long-term socioecological research.
245 citations
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TL;DR: In this article, the authors examined the implications of the distributions of the depths of atmospheric shower maximum (X-max) using a hybrid technique, for composition and hadronic interaction models, and found that their data are not well described by a mix of protons and iron nuclei over most of the energy range.
Abstract: Using the data taken at the Pierre Auger Observatory between December 2004 and December 2012, we have examined the implications of the distributions of depths of atmospheric shower maximum (X-max), using a hybrid technique, for composition and hadronic interaction models. We do this by fitting the distributions with predictions from a variety of hadronic interaction models for variations in the composition of the primary cosmic rays and examining the quality of the fit. Regardless of what interaction model is assumed, we find that our data are not well described by a mix of protons and iron nuclei over most of the energy range. Acceptable fits can be obtained when intermediate masses are included, and when this is done consistent results for the proton and iron-nuclei contributions can be found using the available models. We observe a strong energy dependence of the resulting proton fractions, and find no support from any of the models for a significant contribution from iron nuclei. However, we also observe a significant disagreement between the models with respect to the relative contributions of the intermediate components.
244 citations
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TL;DR: In this article, the authors describe the climatology of the near surface urban heat island of Mexico City, using hourly data from two recently installed automatic stations at a rural and an urban site.
244 citations
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TL;DR: The most important sources of ozone precursors, hydrocarbons and oxides of nitrogen are light-and heavy-duty on-road vehicles and off-road vehicle, utilizing spark and compression ignition engines burning gasoline and diesel respectively as mentioned in this paper.
244 citations
Authors
Showing all 73617 results
Name | H-index | Papers | Citations |
---|---|---|---|
Richard Peto | 183 | 683 | 231434 |
Anton M. Koekemoer | 168 | 1127 | 106796 |
Rory Collins | 162 | 489 | 193407 |
Timothy C. Beers | 156 | 934 | 102581 |
Vivek Sharma | 150 | 3030 | 136228 |
Kjell Fuxe | 142 | 1479 | 89846 |
Prashant V. Kamat | 140 | 725 | 79259 |
Carmen García | 139 | 1503 | 96925 |
Harold A. Mooney | 135 | 450 | 100404 |
Efe Yazgan | 128 | 986 | 79041 |
Roberto Maiolino | 127 | 816 | 61724 |
Peter Nugent | 127 | 754 | 92988 |
William R. Miller | 125 | 601 | 72570 |
Nicholas A. Kotov | 123 | 574 | 55210 |
John C. Wingfield | 122 | 509 | 52291 |