National Autonomous University of Mexico

About: National Autonomous University of Mexico is a education organization based out in Mexico City, Distrito Federal, Mexico. It is known for research contribution in the topics: Population & Galaxy. The organization has 72868 authors who have published 127797 publications receiving 2285543 citations. The organization is also known as: UNAM & Universidad Nacional Autónoma de México.

Production of recombinant proteins: challenges and solutions.

Abstract: Efficient strategies for the production of recombinant proteins are gaining increasing importance, as more applications that require high amounts of high-quality proteins reach the market. Higher production efficiencies and, consequently, lower costs of the final product are needed for obtaining a commercially viable process. In this chapter, common problems in recombinant protein production are reviewed and strategies for their solution are discussed. Such strategies include molecular biology techniques, as well as manipulation of the culture environment. Finally, specific problems relevant to different hosts are discussed.

The incidence of obscuration in active galactic nuclei

Abstract: We study the incidence of nuclear obscuration on a complete sample of 1310 AGN selected on the basis of their rest-frame 2‐10 keV X-ray flux from the XM M-COSMOS survey, in the redshift range 0.3 < z < 3.5. We classify the AGN as obscured or un-obscured on the basis of either the optical spectral properties and the over all SED or the shape of the X-ray spectrum. The two classifications agree in about 70% of the ob jects, and the remaining 30% can be further subdivided into two distinct classes: at low l uminosities X-ray un-obscured AGN do not always show signs of broad lines or blue/UV continuum emission in their optical spectra, most likely due to galaxy dilution effects; a t high luminosities broad line AGN may have absorbed X-ray spectra, which hints at an increased incidence of small-scale (subparsec) dust-free obscuration. We confirm that the fraction of obscured AGN is a decreasing function of the intrinsic X-ray luminosity, while the incid ence of absorption shows significant evolution only for the most luminous AGN, which appear to be more commonly obscured at higher redshift. We find no significant difference between th e mean stellar masses and star formation rates of obscured and un-obscured AGN hosts. We conclude that the physical state of the medium responsible for obscuration in AGN is complex, and mainly determined by the radiation environment (nuclear luminosity) in a small region enclosed within the gravitational sphere of influence of the central black hole, but is la rgely insensitive to the wider scale galactic conditions.