Institution
Sichuan University
Education•Chengdu, China•
About: Sichuan University is a education organization based out in Chengdu, China. It is known for research contribution in the topics: Catalysis & Population. The organization has 107623 authors who have published 102844 publications receiving 1612131 citations. The organization is also known as: Sìchuān Dàxué.
Topics: Catalysis, Population, Medicine, Cancer, Chemistry
Papers published on a yearly basis
Papers
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TL;DR: Psychological interventions that reduce fear and improve sleep durations need to be made available to the home-quarantined university students, and graduating students and those in the worst-hit areas should be given priority focus.
526 citations
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TL;DR: In this article, the morphological control of conductive networks in conductive polymer composites (CPCs) has been extensively investigated as an important issue for the preparation of high performance CPCs.
525 citations
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TL;DR: The aberrant functions of enzymes in DNA methylation, histone acetylation and histone methylation during tumor progression are summarized and the development of inhibitors of or drugs targeted at epigenetic enzymes are highlighted.
Abstract: Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence. Epigenetic dysregulation is often linked to human disease, notably cancer. With the development of various drugs targeting epigenetic regulators, epigenetic-targeted therapy has been applied in the treatment of hematological malignancies and has exhibited viable therapeutic potential for solid tumors in preclinical and clinical trials. In this review, we summarize the aberrant functions of enzymes in DNA methylation, histone acetylation and histone methylation during tumor progression and highlight the development of inhibitors of or drugs targeted at epigenetic enzymes.
523 citations
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TL;DR: A meta-analysis supports the use of multicomponent nonpharmacological delirium prevention interventions to advance acute care for older persons, with a trend toward decreasing length of stay and avoiding institutionalization.
Abstract: MAIN OUTCOMES AND MEASURES We identified 14 interventional studies. The results for outcomes of delirium incidence, falls, length of stay, and institutionalization were pooled for the meta-analysis, but heterogeneity limited our meta-analysis of the results for change in functional or cognitive status. Overall, 11 studies demonstrated significant reductions in delirium incidence (odds ratio [OR], 0.47; 95% CI, 0.38-0.58). Four randomized or matched trials reduced delirium incidence by 44% (OR, 0.56; 95% CI, 0.42-0.76). The rate of falls decreased significantly among intervention patients in 4 studies (OR, 0.38; 95% CI, 0.25-0.60); in 2 randomized or matched trials, the rate of falls was reduced by 64% (OR, 0.36; 95% CI, 0.22-0.61). Length of stay and institutionalization also trended toward decreases in the intervention groups, with a mean difference of −0.16 (95% CI, −0.97 to 0.64) day shorter and the odds of institutionalization 5% lower (OR, 0.95; 95% CI, 0.71-1.26). Among higher-quality randomized or matched trials, length of stay trended −0.33 (95% CI, −1.38 to 0.72) day shorter, and the odds of institutionalization trended 6% lower (OR, 0.94; 95% CI, 0.69-1.30).
521 citations
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TL;DR: The prevailing 3D printing techniques and their most recent applications in building tissue constructs are discussed and 3D bioprinting of vasculature network is particularly discussed for its foremost significance in maintaining tissue viability and promoting functional maturation.
518 citations
Authors
Showing all 108474 results
Name | H-index | Papers | Citations |
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Jie Zhang | 178 | 4857 | 221720 |
Robin M. Murray | 171 | 1539 | 116362 |
Xiang Zhang | 154 | 1733 | 117576 |
Rui Zhang | 151 | 2625 | 107917 |
Xiaoyuan Chen | 149 | 994 | 89870 |
Yi Yang | 143 | 2456 | 92268 |
Xinliang Feng | 134 | 721 | 73033 |
Chuan He | 130 | 584 | 66438 |
Lei Zhang | 130 | 2312 | 86950 |
Jian Zhou | 128 | 3007 | 91402 |
Shaobin Wang | 126 | 872 | 52463 |
Yi Xie | 126 | 745 | 62970 |
Pak C. Sham | 124 | 866 | 100601 |
Wei Chen | 122 | 1946 | 89460 |
Bo Wang | 119 | 2905 | 84863 |