University of Haifa

About: University of Haifa is a education organization based out in Haifa, Israel. It is known for research contribution in the topics: Population & Poison control. The organization has 7558 authors who have published 27141 publications receiving 711629 citations. The organization is also known as: Haifa University & Universiṭat Ḥefah.

Digital inequalities and why they matter

Abstract: While the field of digital inequality continues to expand in many directions, the relationship between digital inequalities and other forms of inequality has yet to be fully appreciated. This article invites social scientists in and outside the field of digital media studies to attend to digital inequality, both as a substantive problem and as a methodological concern. The authors present current research on multiple aspects of digital inequality, defined expansively in terms of access, usage, skills, and self-perceptions, as well as future lines of research. Each of the contributions makes the case that digital inequality deserves a place alongside more traditional forms of inequality in the twenty-first century pantheon of inequalities. Digital inequality should not be only the preserve of specialists but should make its way into the work of social scientists concerned with a broad range of outcomes connected to life chances and life trajectories. As we argue, the significance of digital inequalities is...

High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat

Abstract: The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a maximum lifespan exceeding 30 years. This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole rat. In comparison, a similarly sized house mouse has a maximum lifespan of 4 years. In addition to their longevity, naked mole rats show an unusual resistance to cancer. Multi-year observations of large naked mole-rat colonies did not detect a single incidence of cancer. Here we identify a mechanism responsible for the naked mole rat's cancer resistance. We found that naked mole-rat fibroblasts secrete extremely high-molecular-mass hyaluronan (HA), which is over five times larger than human or mouse HA. This high-molecular-mass HA accumulates abundantly in naked mole-rat tissues owing to the decreased activity of HA-degrading enzymes and a unique sequence of hyaluronan synthase 2 (HAS2). Furthermore, the naked mole-rat cells are more sensitive to HA signalling, as they have a higher affinity to HA compared with mouse or human cells. Perturbation of the signalling pathways sufficient for malignant transformation of mouse fibroblasts fails to transform naked mole-rat cells. However, once high-molecular-mass HA is removed by either knocking down HAS2 or overexpressing the HA-degrading enzyme, HYAL2, naked mole-rat cells become susceptible to malignant transformation and readily form tumours in mice. We speculate that naked mole rats have evolved a higher concentration of HA in the skin to provide skin elasticity needed for life in underground tunnels. This trait may have then been co-opted to provide cancer resistance and longevity to this species.

Sign Language and Linguistic Universals

Abstract: Sign languages are of great interest to linguists, because while they are the product of the same brain, their physical transmission differs greatly from that of spoken languages. In this 2006 study, Wendy Sandler and Diane Lillo-Martin compare sign languages with spoken languages, in order to seek the universal properties they share. Drawing on general linguistic theory, they describe and analyze sign language structure, showing linguistic universals in the phonology, morphology, and syntax of sign language, while also revealing non-universal aspects of its structure that must be attributed to its physical transmission system. No prior background in sign language linguistics is assumed, and numerous pictures are provided to make descriptions of signs and facial expressions accessible to readers. Engaging and informative, Sign Language and Linguistic Universals will be invaluable to linguists, psychologists, and all those interested in sign languages, linguistic theory and the universal properties of human languages.

Field research in conflict environments: Methodological challenges and snowball sampling

Abstract: Conducting research in conflict environments is a challenge, given their complexity and common attitudes of distrust and suspicion. Yet, conflict and methodology are usually analyzed as separate fields of interest. Methodological aspects of field work in conflict environments have not been systematically analyzed. This article addresses the central methodological problems of research conducted in conflict environments. We suggest the use of the snowball sampling method (hereafter, SSM) as an answer to these challenges. The effectiveness of this method has been recognized as significant in a variety of cases, mainly regarding marginalized populations. We claim that in conflict environments, the entire population is marginalized to some degree, making it ‘hidden’ from and ‘hard to reach’ for the outsider researcher. The marginalization explains why it is difficult to locate, access and enlist the cooperation of the research populations, which in a non-conflict context would not have been difficult to do. SS...