University of Nigeria, Nsukka

About: University of Nigeria, Nsukka is a education organization based out in Nsukka, Nigeria. It is known for research contribution in the topics: Population & Health care. The organization has 10211 authors who have published 13685 publications receiving 138922 citations.

Energy consumption, FDI, and urbanization linkage in coastal Mediterranean countries: re-assessing the pollution haven hypothesis

Abstract: Foreign direct investment (FDI) and the consumption of non-renewable energy have been on the increase in the coastal Mediterranean countries (CMCs) over the last few decades. Both trigger growth, but the environmental impact could be far-reaching as environmental distortions are mainly human-induced. This study examines the environmental issues facing CMCs. Specifically, we investigate whether the pollution haven hypothesis holds for CMCs. We employ a quantile panel data analysis for CMCs to account for heterogeneity and distributional effects of socioeconomic factors. The result reveals that the influence of FDI on environmental degradation is a function of the indicators utilized and also depends on the initial levels of environmental degradation. The results suggest that the pollution haven hypothesis does not hold for CMCs. However, we also find that energy consumption significantly increases environmental degradation for all indicators and across the observed quantiles. The effects of economic growth and urbanization on the environment were mixed for the different indicators and across quantiles. We recommend that it is pertinent for CMCs to limit their "dirty" energy sources and substitute them with renewables to promote environmental sustainability.

Nanovesicular carriers as alternative drug delivery systems: ethosomes in focus.

Abstract: Introduction: The application of vesicular carrier formulations has generated promise of overcoming some problems associated with drug delivery arising from not only the physicochemical properties of the drug but also those of the biological barriers, such as the membrane linings of various body tissues and the skin. This review article discusses the importance of various vesicular carriers, namely liposomes, niosomes, transfersomes and ethosomes in drug delivery with greater emphasis on ethosomes. Areas covered: The nature, mechanism of drug delivery, methods of preparation as well as characterization of vesicular carriers was discussed with a focus on ethosomes. An overview of their potential applications was provided with discussions on the future prospects and challenges of achieving enhanced drug delivery using ethosomes. Expert opinion: Vesicular carriers offer controlled and sustained drug release, improved permeability and protection of the encapsulated bioactives. Ethosomes offer more efficient a...

A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in West Africans The Africa America Diabetes Mellitus (AADM) Study

Abstract: The incidence of type 2 diabetes is growing rapidly, not only in developed countries but also worldwide. We chose to study type 2 diabetes in West Africa, where diabetes is less common than in the U.S., reasoning that in an environment where calories are less abundant, incident cases of type 2 diabetes might carry a proportionately greater genetic component. Through the Africa America Diabetes Mellitus (AADM) study, we carried out a genome-wide linkage analysis of type 2 diabetes in a cohort of 343 affected sibling pairs (691 individuals) enrolled from five West African centers in two countries (Ghana: Accra and Kumasi; Nigeria: Enugu, Ibadan, and Lagos). A total of 390 polymorphic markers were genotyped, and multipoint linkage analysis was conducted using the GENEHUNTER-PLUS and ASM programs. Suggestive evidence of linkage was observed in four regions on three chromosomes (12, 19, and 20). The two largest logarithm of odds scores of 2.63 and 1.92 for chromosomes 20q13.3 and 12q24, respectively, are particularly interesting because these regions have been reported to harbor diabetes susceptibility genes in several other populations and ethnic groups. Given the history of forced migration of West African populations during the slave trade, these results should have considerable relevance to the study of type 2 diabetes in African Americans.