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Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use
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Caffeine is the most widely consumed behaviorally active substance in the world and almost all caffeine comes from dietary sources (beverages and food).Abstract:
Caffeine is the most widely consumed behaviorally active substance in the world. Almost all caffeine comes from dietary sources (beverages and food), most of it from coffee and tea. Acute and, especially, chronic caffeine intake appear to have only minor negative consequences on health. For thisread more
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Grape stalk application for caffeine removal through adsorption.
TL;DR: This study investigated the employability of grape stalk, a waste from grape industrialization process without effective use, in caffeine removal from aqueous solution and found it viable, combining removal efficiency, low cost and biodegradability of the material applied.
Journal ArticleDOI
Neuroprotective effects of caffeine in the model of 6-hydroxydopamine lesion in rats.
Lissiana Magna Vasconcelos Aguiar,Hélio Vitoriano Nobre,Danielle Silveira Macêdo,Aline A. Oliveira,Rivelilson Mendes de Freitas,Silvânia Maria Mendes Vasconcelos,Geanne M. A. Cunha,Francisca Cléa Florenço de Sousa,Glauce Socorro de Barros Viana +8 more
TL;DR: The data demonstrated beneficial effects of caffeine in this model of PD, suggesting the potential use of A2A antagonists as a novel treatment for this neurodegenerative disease.
Journal ArticleDOI
Caffeine: behavioral effects of withdrawal and related issues.
TL;DR: It is suggested that the evidence leads to the conclusion that non pharmacological factors related to knowledge and expectation are the prime determinants of symptoms and their reported prevalence on withdrawal of caffeine after regular consumption.
Journal ArticleDOI
Adenosine A2A receptors are necessary and sufficient to trigger memory impairment in adult mice
Natália Pagnussat,Amanda Staldoni Almeida,Daniela M. Marques,Fernanda Nunes,G C Chenet,Paulo Henrique S. Botton,Sabrina Mioranzza,C M Loss,Rodrigo A. Cunha,Lisiane O. Porciúncula +9 more
TL;DR: Caffeine (a non‐selective adenosine receptor antagonist) prevents memory deficits in aging and Alzheimer's disease, an effect mimicked byadenosine A2A receptor, but not A1 receptor, antagonists.
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Caffeine Consumption through Coffee: Content in the Beverage, Metabolism, Health Benefits and Risks
Juliana dePaula,Adriana Farah +1 more
TL;DR: Caffeine exerts positive effects in the body, often in association with other substances, contributing to prevention of several chronic diseases and the potential adverse effects have also been extensively studied in animal species and in humans.
References
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IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
TL;DR: This timely monograph is a distillation of knowledge of hepatitis B, C and D, based on a review of 1000 studies by a small group of scientists, and it is concluded that hepatitis D virus cannot be classified as a human carcinogen.
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A Neural Substrate of Prediction and Reward
TL;DR: Findings in this work indicate that dopaminergic neurons in the primate whose fluctuating output apparently signals changes or errors in the predictions of future salient and rewarding events can be understood through quantitative theories of adaptive optimizing control.