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Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use

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TLDR
Caffeine is the most widely consumed behaviorally active substance in the world and almost all caffeine comes from dietary sources (beverages and food).
Abstract
Caffeine is the most widely consumed behaviorally active substance in the world. Almost all caffeine comes from dietary sources (beverages and food), most of it from coffee and tea. Acute and, especially, chronic caffeine intake appear to have only minor negative consequences on health. For this

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References
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Journal ArticleDOI

Physical dependence increases the relative reinforcing effects of caffeine versus placebo

TL;DR: Findings provide the strongest evidence to date indicating that caffeine physical dependence increases the relative reinforcing effects of caffeine versus placebo.
Journal ArticleDOI

Effect of decaffeinated versus regular coffee on blood pressure. A 12-week, double-blind trial.

TL;DR: It is concluded that in normotensive adults replacement of regular by decaffeinated coffee leads to a real but small fall in blood pressure, however, it remains to be established whether a mass switch from regular to decaffinated coffee would significantly reduce the total incidence of hypertension-related disorders.
Book ChapterDOI

Tea: the plant and its manufacture; chemistry and consumption of the beverage.

TL;DR: In this paper, a complete understanding of the chemistry of the mass of oxidized phenolic material, commonly known as thearubigens but better classified as unknown polyphenols, is presented.
Journal ArticleDOI

Behavioral and physiological effects of xanthines in nonhuman primates.

TL;DR: Converging lines of evidence suggest that adenosine A2 and cAMP-specific PDE mechanisms play especially prominent roles in mediating the behavioral and physiological effects of xanthines in nonhuman primates.
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Trending Questions (1)
Does caffeine consumption limit the blood supply to the brain?

No, caffeine consumption does not limit the blood supply to the brain.