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Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use
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Caffeine is the most widely consumed behaviorally active substance in the world and almost all caffeine comes from dietary sources (beverages and food).Abstract:
Caffeine is the most widely consumed behaviorally active substance in the world. Almost all caffeine comes from dietary sources (beverages and food), most of it from coffee and tea. Acute and, especially, chronic caffeine intake appear to have only minor negative consequences on health. For thisread more
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References
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Journal ArticleDOI
Does Caffeine Enhance or Merely Restore Degraded Psychomotor Performance
Journal Article
Caffeine and schizophrenia.
TL;DR: Two cases are described in which markedly increased consumption of caffeine led to an exacerbation of a schizophrenic process and the clinical and research implications are discussed in light of the clinicaland research implications.
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Reinforcing properties of caffeine: Studies in humans and laboratory animals
TL;DR: These studies show that, under appropriate conditions, caffeine can serve as a reinforcer and can produce elevations in subjective drug liking and/or euphoria and suggest that physical dependence substantially potentiates the reinforcing effects of caffeine.
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The Effects of Caffeine and Aspirin on Mood and Performance
TL;DR: It is demonstrated that the addition of caffeine to aspirin, in a dose commonly employed in over-the-counter drugs, has significant beneficial consequences with respect to mood and performance.
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Adenosine A1 Receptor-mediated Modulation of Dopamine D1 Receptors in Stably Cotransfected Fibroblast Cells
Sergi Ferré,Maria Torvinen,Katerina Antoniou,Eva Irenius,Olivier Civelli,Ernest Arenas,Bertil B. Fredholm,Kjell Fuxe +7 more
TL;DR: The results suggest that adenosine A1 receptors antagonistically modulate dopamine D1 receptors at the level of receptor binding and the generation of second messengers.