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Open AccessJournal ArticleDOI

Acute Hepatitis E Infection Accounts for Some Cases of Suspected Drug-Induced Liver Injury

Timothy Davern, +13 more
- 01 Nov 2011 - 
- Vol. 141, Iss: 5, pp 1665-1672
TLDR
HEV infection contributes to a small but important proportion of cases of acute liver injury that are suspected to be drug induced, andSerologic testing for HEV infection should be performed, particularly if clinical features are compatible with acute viral hepatitis.
About: 
This article is published in Gastroenterology.The article was published on 2011-11-01 and is currently open access. It has received 295 citations till now. The article focuses on the topics: Hepatitis E & Viral hepatitis.

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Citations
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Journal ArticleDOI

Comparison of Liver Biopsy Findings with the Digestive Disease Week Japan 2004 Scale for Diagnosis of Drug-Induced Liver Injury

Akemi Tsutsui, +8 more
- 01 Nov 2015 - 
TL;DR: The liver biopsy findings and DDW-J scale were well correlated, and the hepatocellular type of liver injuries was well coincided by both evaluations, though there were several discrepant cases, particularly in cholestatic type.
Journal ArticleDOI

The Unmet Needs of Hepatitis E Virus Diagnosis in Suspected Drug-Induced Liver Injury in Limited Resource Setting.

Mohamed A El-Mokhtar, +10 more
- 01 Jan 2021 - 
TL;DR: In this article, a putative threshold for liver function parameters was determined for drug-induced liver injury (DILI) diagnosis based on the exclusion of other causes of liver dysfunction and the recognition of potential causative drugs.
Journal ArticleDOI

Exacerbation of hepatitis E virus infection during anti-TNFα treatment.

Patrick Behrendt, +10 more
- 01 Mar 2017 - 
TL;DR: A case of severe exacerbation of a chronic HEV infection in a patient undergoing treatment with a TNFα-inhibitor for psoriatic arthritis despite potent anti-HEV T-cell responses is described.
Journal ArticleDOI

Multikinase inhibitor-induced liver injury in patients with cancer: A review for clinicians.

Camille Houron, +6 more
- 01 Jan 2021 - 
TL;DR: All MKIs can potentially cause liver injury, which is sometimes irreversible, and as there is still no strategy available to prevent MKI-related hepatotoxicity, early detection remains crucial.
Journal ArticleDOI

Successful extracorporeal liver dialysis for the treatment of trimethoprim-sulfamethoxazole-induced fulminant hepatic failure.

Choon Ta Ng, +3 more
- 01 May 2013 - 
TL;DR: A 17-year-old Chinese male adolescent who presented with fever, myalgia, generalised maculopapular rash and lymphadenopathy after taking TMP-SMZ for acne vulgaris subsequently developed hepatic encephalopathy and was worked up for urgent liver transplantation.
References
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Journal ArticleDOI

Causality assessment of adverse reactions to drugs--I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries.

Gaby Danan, +1 more
- 01 Nov 1993 - 
TL;DR: In this paper, a new method for drug causality assessment is described and applied to reports of acute liver injuries, using reports with positive rechallenge as external standard.
Journal ArticleDOI

Hepatitis E virus and chronic hepatitis in organ-transplant recipients.

Nassim Kamar, +13 more
- 21 Feb 2008 - 
TL;DR: The time from transplantation to diagnosis was significantly shorter and the total counts of lymphocytes and of CD2, CD3, and CD4 T cells were significantly lower in patients in whom chronic disease developed.
Journal ArticleDOI

A novel virus in swine is closely related to the human hepatitis E virus

Xiang-Jin Meng, +8 more
- 02 Sep 1997 - 
TL;DR: The discovery of swine HEV not only has implications for HEV vaccine development, diagnosis, and biology, but also raises a potential public health concern for zoonosis or xenozoonosis following xenotransplantation with pig organs.
Journal ArticleDOI

Hepatitis E virus.

Suzanne U. Emerson, +1 more
- 01 May 2003 - 
TL;DR: Hepatitis E virus is an enterically transmitted virus that causes both epidemics and sporadic cases of acute hepatitis in many countries of Asia and Africa but only rarely causes disease in more industrialised countries.
Journal ArticleDOI

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

Naga Chalasani, +9 more
- 01 Dec 2008 - 
TL;DR: This report summarizes the causes, clinical features, and outcomes from the first 300 patients enrolled in a prospective study to recruit patients with suspected idiosyncratic drug-induced liver injury and create a repository of biological samples for analysis.
Related Papers (5)

Hepatitis E virus and chronic hepatitis in organ-transplant recipients.

Nassim Kamar, +13 more
- 21 Feb 2008 - 

Causality assessment of adverse reactions to drugs--I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries.

Gaby Danan, +1 more
- 01 Nov 1993 - 

Drug-Induced Liver Injury: An Analysis of 461 Incidences Submitted to the Spanish Registry Over a 10-Year Period

Raúl J. Andrade, +19 more
- 01 Aug 2005 - 

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

Naga Chalasani, +9 more
- 01 Dec 2008 - 

Drug-induced acute liver failure: results of a U.S. multicenter, prospective study.

Adrian Reuben, +2 more
- 01 Dec 2010 -