Journal ArticleDOI
Brain Connectivity: Gender Makes a Difference
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TLDR
The literature provides convergent evidence for a substantial gender difference in brain connectivity within the human brain that possibly underlies gender-related cognitive differences and should be mandatory to take gender into account when designing experiments or interpreting results of brain connectivity/network in health and disease.Abstract:
It has been well known that gender plays a critical role in the anatomy and function of the human brain, as well as human behaviors. Recent neuroimaging studies have demonstrated gender effects on not only focal brain areas but also the connectivity between areas. Specifically, structural MRI and diffusion MRI data have revealed substantial gender differences in white matter-based anatomical connectivity. Structural MRI data further demonstrated gender differences in the connectivity revealed by morphometric correlation among brain areas. Functional connectivity derived from functional neuroimaging (e.g., functional MRI and PET) data is also modulated by gender. Moreover, male and female human brains display differences in the network topology that represents the organizational patterns of brain connectivity across the entire brain. In this review, the authors summarize recent findings in the multimodal brain connectivity/network research with gender, focusing on large-scale data sets derived from modern neuroimaging techniques. The literature provides convergent evidence for a substantial gender difference in brain connectivity within the human brain that possibly underlies gender-related cognitive differences. Therefore, it should be mandatory to take gender into account when designing experiments or interpreting results of brain connectivity/network in health and disease. Future studies will likely be conducted to explore the interdependence between gender-related brain connectivity/network and the gender-specific nature of brain diseases as well as to investigate gender-related characteristics of multimodal brain connectivity/network in the normal brain.read more
Citations
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Neurodevelopmental changes in the relationship between stress perception and prefrontal-amygdala functional circuitry.
Jingsong Wu,Xiujuan Geng,Robin Shao,Nichol M.L. Wong,Jing Tao,Lidian Chen,Chetwyn C.H. Chan,Tatia M.C. Lee +7 more
TL;DR: The relationship between perceived stress and resting-state neural connectivity patterns among 67 healthy volunteers belonging to three age groups, who were supposed to be at separate neurodevelopmental phases and exhibit different affect regulatory processes in the brain, was examined.
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Neural correlates of emotion processing comparing antidepressants and exogenous oxytocin in postpartum depressed women: An exploratory study.
TL;DR: Postpartum depressed women’s neural activation in areas identified as important to emotion and reward processing and potentially, antidepressant response: the amygdala, nucleus accumbens and ventral tegmental area is explored.
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White matter deficits in cocaine use disorder: convergent evidence from in vivo diffusion tensor imaging and ex vivo proteomic analysis.
Lucca Pizzato Tondo,Thiago Wendt Viola,Gabriel Rodrigo Fries,Bruno Kluwe-Schiavon,Leonardo Mello Rothmann,Renata B. Cupertino,Pedro Maria Abreu Ferreira,Alexandre Rosa Franco,Scott D. Lane,Laura Stertz,Zhongming Zhao,Ruifeng Hu,Thomas Meyer,Joy M. Schmitz,Consuelo Walss-Bass,Rodrigo Grassi-Oliveira,Rodrigo Grassi-Oliveira +16 more
TL;DR: In this article, the authors performed an ex vivo large-scale proteomic analysis using liquid chromatography-tandem mass spectrometry in postmortem brains of patients with chronic cocaine use disorder (CUD) and healthy controls.
Journal ArticleDOI
EEG-based functional brain networks: hemispheric differences in males and females
TL;DR: It is found that male brains have significantly greater global efficiency across all frequency bands for a wide range of cost values in both hemispheres, and female brains showed significantly greater right-hemispheric local efficiency than male brains.
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Shared functional connections within and between cortical networks predict cognitive abilities in adult males and females.
TL;DR: In this article, the authors evaluate sex-independent and sex-specific relationships between functional connectivity and individual cognitive abilities in 392 healthy young adults (196 males) from the Human Connectome Project and reveal that largely overlapping connections between visual, dorsal attention, ventral attention, and temporal parietal networks are associated with better performance on crystallised and fluid cognitive tests in males and females.
References
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