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False-Positive Psychology: Undisclosed Flexibility in Data Collection and Analysis Allows Presenting Anything as Significant

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TLDR
It is shown that despite empirical psychologists’ nominal endorsement of a low rate of false-positive findings, flexibility in data collection, analysis, and reporting dramatically increases actual false- positive rates, and a simple, low-cost, and straightforwardly effective disclosure-based solution is suggested.
Abstract
In this article, we accomplish two things. First, we show that despite empirical psychologists' nominal endorsement of a low rate of false-positive findings (≤ .05), flexibility in data collection, analysis, and reporting dramatically increases actual false-positive rates. In many cases, a researcher is more likely to falsely find evidence that an effect exists than to correctly find evidence that it does not. We present computer simulations and a pair of actual experiments that demonstrate how unacceptably easy it is to accumulate (and report) statistically significant evidence for a false hypothesis. Second, we suggest a simple, low-cost, and straightforwardly effective disclosure-based solution to this problem. The solution involves six concrete requirements for authors and four guidelines for reviewers, all of which impose a minimal burden on the publication process.

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Improving basic and translational science by accounting for litter-to-litter variation in animal models

TL;DR: Litter effects are common, large, and ignoring them can make replication of findings difficult and can contribute to the low rate of translating preclinical in vivo studies into successful therapies.
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An Introduction to Bayesian Hypothesis Testing for Management Research

TL;DR: In contrast to pNHST, Bayes factors allow researchers to quantify evidence in favor of the null hypothesis and do not require adjustment for the intention with which the data were collected as discussed by the authors.
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Testing Prospective Effects in Longitudinal Research: Comparing Seven Competing Cross-Lagged Models

TL;DR: Examining the association between low self-esteem and depression as a case study, seven competing longitudinal models in 10 samples were examined and the traditional CLPM and the random intercepts cross-lagged panel model (RI-CLPM) converged in every sample, whereas the other models frequently failed to converge or did not converge properly.
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Replication in Psychological Science

TL;DR: Brian Nosek reported direct replication attempts of 100 experiments published in prestigious psychology journals in 2008, including experiments reported in 39 articles in Psychological Science, and found that fewer than half of them yielded a statistically significant effect.
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Performing High-Powered Studies Efficiently With Sequential Analyses

TL;DR: Sequential analyses as discussed by the authors can greatly improve the efficiency with which data are collected and provide an efficient way to perform high-powered informative experiments, which can be used in large-scale medical trials and provide a practical primer that allows researchers to incorporate sequential analyses in their research.
References
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Journal ArticleDOI

The case for motivated reasoning.

TL;DR: It is proposed that motivation may affect reasoning through reliance on a biased set of cognitive processes--that is, strategies for accessing, constructing, and evaluating beliefs--that are considered most likely to yield the desired conclusion.

Why Most Published Research Findings Are False

TL;DR: In this paper, the authors discuss the implications of these problems for the conduct and interpretation of research and suggest that claimed research findings may often be simply accurate measures of the prevailing bias.
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Group sequential methods in the design and analysis of clinical trials

TL;DR: In this article, a group sequential design is proposed to divide patient entry into a number of equal-sized groups so that the decision to stop the trial or continue is based on repeated significance tests of the accumulated data after each group is evaluated.
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Measuring the Prevalence of Questionable Research Practices With Incentives for Truth Telling

TL;DR: It is found that the percentage of respondents who have engaged in questionable practices was surprisingly high, which suggests that some questionable practices may constitute the prevailing research norm.
Journal ArticleDOI

Attribution of success and failure revisited, or: The motivational bias is alive and well in attribution theory

TL;DR: The authors found that self-serving effects for both success and failure are obtained in most but not all experimental paradigms, and that these attributions are better understood in motivational than in information-processing terms.
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