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False-Positive Psychology: Undisclosed Flexibility in Data Collection and Analysis Allows Presenting Anything as Significant

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TLDR
It is shown that despite empirical psychologists’ nominal endorsement of a low rate of false-positive findings, flexibility in data collection, analysis, and reporting dramatically increases actual false- positive rates, and a simple, low-cost, and straightforwardly effective disclosure-based solution is suggested.
Abstract
In this article, we accomplish two things. First, we show that despite empirical psychologists' nominal endorsement of a low rate of false-positive findings (≤ .05), flexibility in data collection, analysis, and reporting dramatically increases actual false-positive rates. In many cases, a researcher is more likely to falsely find evidence that an effect exists than to correctly find evidence that it does not. We present computer simulations and a pair of actual experiments that demonstrate how unacceptably easy it is to accumulate (and report) statistically significant evidence for a false hypothesis. Second, we suggest a simple, low-cost, and straightforwardly effective disclosure-based solution to this problem. The solution involves six concrete requirements for authors and four guidelines for reviewers, all of which impose a minimal burden on the publication process.

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How does cannabidiol (CBD) influence the acute effects of delta-9-tetrahydrocannabinol (THC) in humans? A systematic review

TL;DR: It is suggested that CBD may interact with some acute effects of THC, and there was considerable heterogeneity in dose, route of administration and THC:CBD ratio across studies and no clear dose-response profile emerged.
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On the Reproducibility of Psychological Science

TL;DR: The results of this reanalysis provide a compelling argument for both increasing the threshold required for declaring scientific discoveries and for adopting statistical summaries of evidence that account for the high proportion of tested hypotheses that are false.
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Statistical Rituals: The Replication Delusion and How We Got There:

TL;DR: In this paper, the authors draw attention to a complementary internal factor, i.e., the strategic game hypothesis, which has been attributed to misguided external incentives gamed by researchers (the strategic-game hypothesis hypothesis).
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A Practical Guide for Improving Transparency and Reproducibility in Neuroimaging Research.

TL;DR: This article aims to be a practical guide for researchers at any stage of their careers that will help them make their research more reproducible and transparent while minimizing the additional effort that this might require.
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Increased objectively assessed vigorous-intensity exercise is associated with reduced stress, increased mental health and good objective and subjective sleep in young adults.

TL;DR: Evidence is provided that meeting the VPA standards of the ACSM is associated with improved mental health and more successful coping among young people, even compared to those who are meeting or exceeding the requirements for MPA.
References
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Journal ArticleDOI

The case for motivated reasoning.

TL;DR: It is proposed that motivation may affect reasoning through reliance on a biased set of cognitive processes--that is, strategies for accessing, constructing, and evaluating beliefs--that are considered most likely to yield the desired conclusion.

Why Most Published Research Findings Are False

TL;DR: In this paper, the authors discuss the implications of these problems for the conduct and interpretation of research and suggest that claimed research findings may often be simply accurate measures of the prevailing bias.
Journal ArticleDOI

Group sequential methods in the design and analysis of clinical trials

TL;DR: In this article, a group sequential design is proposed to divide patient entry into a number of equal-sized groups so that the decision to stop the trial or continue is based on repeated significance tests of the accumulated data after each group is evaluated.
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Measuring the Prevalence of Questionable Research Practices With Incentives for Truth Telling

TL;DR: It is found that the percentage of respondents who have engaged in questionable practices was surprisingly high, which suggests that some questionable practices may constitute the prevailing research norm.
Journal ArticleDOI

Attribution of success and failure revisited, or: The motivational bias is alive and well in attribution theory

TL;DR: The authors found that self-serving effects for both success and failure are obtained in most but not all experimental paradigms, and that these attributions are better understood in motivational than in information-processing terms.
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