GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
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The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.Abstract:
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwideread more
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Guidelines on Renal Cell Carcinoma
Börje Ljungberg,D.C. Hanbury,Markus A. Kuczyk,Axel S. Merseburger,Peter F.A. Mulders,J-J. Patard,Ioanel C. Sinescu +6 more
TL;DR: The use of imaging techniques such as ultrasound (US) and computed tomography (CT) has increased the detection of asymptomatic renal cell cancer (RCC) and the most effective prophylaxis is to avoid cigarette smoking and obesity.
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EAACI/GA(2)LEN/EDF/WAO guideline: management of urticaria.
Torsten Zuberbier,Riccardo Asero,Carsten Bindslev-Jensen,G. Walter Canonica,Martin K. Church,Ana Giménez-Arnau,Clive Grattan,Alexander Kapp,Marcus Maurer,Hans F. Merk,Barbara Rogala,Sarbjit S. Saini,Mario Sánchez-Borges,Peter Schmid-Grendelmeier,Holger J. Schünemann,Petra Staubach,Gino A. Vena,Bettina Wedi +17 more
TL;DR: This guideline has a profound impact on the quality of life and effective treatment is, therefore, required and the recommended first line treatment is new generation, nonsedating H1‐antihistamines, and second‐line therapies should be added to the antihistamine treatment.
International Cancer of Pancreas Screening (CAPS) Consortium. International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer.
Mi Canto,Femme Harinck,Rh Hruban,Gj Offerhaus,Jw Poley,Ihab R. Kamel,Yung Nio,Rs Schulick,Claudio Bassi,Irma Kluijt,Mj Levy,Amitabh Chak,Paul Fockens,M. Goggins,Miguel Bruno +14 more
TL;DR: Screening is recommended for high-risk individuals, but more evidence is needed, particularly for how to manage patients with detected lesions, particularly at high-volume centres with multidisciplinary teams.
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Anaesthesia for hip fracture surgery in adults
TL;DR: There was insufficient evidence available from trials comparing regional versus general anaesthesia to rule out clinically important differences, but regional anaesthesia may reduce acute postoperative confusion but no conclusions can be drawn for mortality or other outcomes.
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David Atkins,Martin P Eccles,Signe Flottorp,Gordon H. Guyatt,David Henry,Suzanne Hill,Alessandro Liberati,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Holger J. Schünemann,Tessa Tan-Torres Edejer,Gunn Elisabeth Vist,John W Williams +14 more
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