GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
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The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.Abstract:
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwideread more
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HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology
Angela N. Bartley,Mary Kay Washington,Christina B. Ventura,Nofisat Ismaila,Carol Colasacco,Al B. Benson,Alfredo Carrato,Margaret L. Gulley,Dhanpat Jain,Sanjay Kakar,Helen Mackay,Catherine J. Streutker,Laura H. Tang,Megan L. Troxell,Jaffer A. Ajani +14 more
TL;DR: This guideline provides specific recommendations for assessment of HER2 in patients with advanced GEA while addressing pertinent technical issues and clinical implications of the results.
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Effects of Housing First approaches on health and well-being of adults who are homeless or at risk of homelessness: systematic review and meta-analysis of randomised controlled trials.
TL;DR: Housing First approaches successfully improve housing stability and may improve some aspects of health, and implementation of HF would likely reduce homelessness and non-routine health service use without an increase in problematic substance use.
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Reporting of Adverse Events in Published and Unpublished Studies of Health Care Interventions: A Systematic Review.
TL;DR: There is strong evidence that much of the information on adverse events remains unpublished and that the number and range of adverse events is higher in unpublished than in published versions of the same study.
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Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies
Ingrid Toews,Szimonetta Lohner,Daniela Küllenberg de Gaudry,Harriet Sommer,Joerg J Meerpohl,Joerg J Meerpohl +5 more
TL;DR: Most health outcomes did not seem to have differences between the NSS exposed and unexposed groups, and future studies should assess the effects of NSSs with an appropriate intervention duration.
Journal ArticleDOI
Presentation, diagnosis, and medical management of heart failure in children: Canadian Cardiovascular Society guidelines.
Paul F. Kantor,Paul F. Kantor,Jane Lougheed,Adrian Dancea,Michael McGillion,Nicole Barbosa,Carol Chan,Rejane Dillenburg,Joseph Atallah,Holger Buchholz,Catherine Chant-Gambacort,J. Conway,J. Conway,Letizia Gardin,Kristen George,Steven C. Greenway,Derek G. Human,Aamir Jeewa,Jack F. Price,Robert D. Ross,S. Lucy Roche,Lindsay M. Ryerson,Reeni Soni,Judith Wilson,Kenny K. Wong,Sarah Bowdin,Charles E. Canter,Christian Drolet,Melanie D. Everitt,Mark K. Friedberg,Lars Grosse-Wortmann,Daphne T. Hsu,John L. Jefferies,Ashok Kakadekar,Seema Mital,Beth Kauffman,Robert S. McKelvie,Elfriede Pahl,J.E. Potts,Julian Raiman,Suryakant Shah,Elizabeth A. Stephenson,Thomasin Adams-Webber,Michelle M. Graham +43 more
TL;DR: In this paper, the authors present guidelines for the recognition, diagnosis, and early medical management of pediatric heart failure in infancy, childhood, and adolescence, which are intended to assist practitioners in office-based or emergency room practice, who encounter children with undiagnosed heart disease and symptoms of possible HF.
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David Atkins,Martin P Eccles,Signe Flottorp,Gordon H. Guyatt,David Henry,Suzanne Hill,Alessandro Liberati,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Holger J. Schünemann,Tessa Tan-Torres Edejer,Gunn Elisabeth Vist,John W Williams +14 more
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