GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
Reads0
Chats0
TLDR
The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.Abstract:
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwideread more
Citations
More filters
Journal ArticleDOI
World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines
Alessandro Fiocchi,Jan L. Brozek,Holger J. Schünemann,Sami L. Bahna,Andrea von Berg,Kirsten Beyer,Martin Bozzola,Julia Bradsher,Enrico Compalati,M. Ebisawa,María Antonieta Guzmán,Haiqi Li,Ralf G. Heine,Paul K. Keith,Gideon Lack,Massimo Landi,Alberto Maria Martelli,F. Rancé,Hugh A. Sampson,Airton Tetelbom Stein,Luigi Terracciano,Stefan Vieths +21 more
TL;DR: The WAO Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines was planned to provide physicians everywhere with a management tool to deal with CMA from suspicion to treatment and to relieve the burden of issues through an ongoing and collective effort of more interactive debate and integrated learning.
Journal ArticleDOI
American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism.
Thomas L. Ortel,Ignacio Neumann,Walter Ageno,Rebecca J. Beyth,Rebecca J. Beyth,Nathan P. Clark,Adam Cuker,Barbara A. Hutten,Michael R. Jaff,Veena Manja,Veena Manja,Sam Schulman,Sam Schulman,Caitlin Thurston,Suresh Vedantham,Peter Verhamme,Daniel M. Witt,Ivan D. Florez,Ivan D. Florez,Ariel Izcovich,Robby Nieuwlaat,Stephanie Ross,Holger J. Schünemann,Wojtek Wiercioch,Yuan Zhang,Yuqing Zhang +25 more
TL;DR: Recommendations include the use of thrombolytic therapy for patients with PE and hemodynamic compromise, use of an international normalized ratio (INR) range, and a preference for direct oral anticoagulants over VKA for primary treatment of VTE.
Journal ArticleDOI
IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults
Anthony W. Chow,Michael S. Benninger,Itzhak Brook,Jan Brozek,Ellie J. C. Goldstein,Lauri A. Hicks,George A. Pankey,Mitchel J. Seleznick,Gregory A. Volturo,Ellen R. Wald,Thomas M. File,Thomas M. File,R. M. Alden +12 more
TL;DR: In this article, evidence-based guidelines for the diagnosis and initial management of suspected acute bacterial rhinosinusitis in adults and children were prepared by a multidisciplinary expert panel of the Infectious Diseases Society of America comprising clinicians and investigators representing internal medicine, pediatrics, emergency medicine, otolaryngology, public health, epidemiology and adult and pediatric infectious disease specialties.
Journal ArticleDOI
Вроджена гіперплазія надниркових залоз внаслідок дефіциту 21-гідроксилази. Клінічні практичні настанови Ендокринологічного Товариства. Частина 1
TL;DR: In this article, the authors propose a new approach for the detection of thyroid cancer using a blood test, which is based on a combination of immunoglobulin and glucosinoline.
Journal ArticleDOI
2014 European Thyroid Association Guidelines for the Management of Subclinical Hypothyroidism in Pregnancy and in Children
John H. Lazarus,Rosalind S. Brown,Chantal Daumerie,Alicja Hubalewska-Dydejczyk,Roberto Negro,Bijay Vaidya +5 more
TL;DR: This guideline has been produced as the official statement of the European Thyroid Association guideline committee and indicates that targeted antenatal screening for thyroid function will miss a substantial percentage of women with thyroid dysfunction.
References
More filters
Journal ArticleDOI
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
Jacques E. Rossouw,Garnet L. Anderson,Ross L. Prentice,Andrea Z. LaCroix,Charles Kooperberg,Marcia L. Stefanick,Rebecca D. Jackson,Shirley A.A. Beresford,Barbara V. Howard,Karen C. Johnson,Jane Morley Kotchen,Judith K. Ockene +11 more
TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
Journal ArticleDOI
Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women
Stephen B. Hulley,Deborah Grady,Trudy L. Bush,Curt D Furberg,David M. Herrington,Betty Riggs,Eric Vittinghoff +6 more
TL;DR: Treatment with oral conjugated equine estrogen plus medroxyprogesterone acetate did not reduce the overall rate of CHD events in postmenopausal women with established coronary disease and the treatment did increase the rate of thromboembolic events and gallbladder disease.
Journal ArticleDOI
Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.
Echt Ds,Philip R. Liebson,Mitchell Lb,Robert W. Peters,Obias-Manno D,Barker Ah,Arensberg D,Baker A,Lawrence S. Friedman,Greene Hl +9 more
TL;DR: There was an excess of deathsDue to arrhythmia and deaths due to shock after acute recurrent myocardial infarction in patients treated with encainide or flecainide.
Journal ArticleDOI
A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction.
TL;DR: Finding and analyzing all therapeutic trials in a given field has become such a difficult and specialized task that the clinical experts called on to summarize the evidence in a timely fashion need access to better databases and new statistical techniques to assist them.
Journal ArticleDOI
Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group.
David Atkins,Martin P Eccles,Signe Flottorp,Gordon H. Guyatt,David Henry,Suzanne Hill,Alessandro Liberati,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Holger J. Schünemann,Tessa Tan-Torres Edejer,Gunn Elisabeth Vist,John W Williams +14 more
TL;DR: The objective was to critically appraise six prominent systems for grading levels of evidence and the strength of recommendations as a basis for agreeing on characteristics of a common, sensible approach.