GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
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The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.Abstract:
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwideread more
Citations
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American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients
Holger J. Schünemann,Mary Cushman,Allison Burnett,Susan R. Kahn,Jan Beyer-Westendorf,Frederick A. Spencer,Suely M. Rezende,Neil A. Zakai,Kenneth A. Bauer,Francesco Dentali,Jill Lansing,Sara Balduzzi,Andrea Darzi,Gian Paolo Morgano,Ignacio Neumann,Ignacio Neumann,Robby Nieuwlaat,Juan José Yepes-Nuñez,Yuan Zhang,Wojtek Wiercioch +19 more
TL;DR: These evidence-based guidelines from the American Society of Hematology intend to support patients, clinicians, and others in decisions about preventing VTE in medical inpatients and outpatients with minor injuries and long-distance travelers.
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International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti-infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).
Brian T. Tsuji,Jason M. Pogue,Alexandre P. Zavascki,Mical Paul,Mical Paul,George L. Daikos,Alan Forrest,Daniele Roberto Giacobbe,Claudio Viscoli,Helen Giamarellou,Ilias Karaiskos,Donald Kaye,Johan W. Mouton,Vincent H. Tam,Visanu Thamlikitkul,Richard G. Wunderink,Jian Li,Roger L. Nation,Keith S Kaye +18 more
TL;DR: In this paper, the authors report consensus therapeutic guidelines for agent selection and dosing of colistin and polymyxin antibiotics for optimal use in adult patients, as endorsed by the American College of Clinical Pharmacy (ACCP), Infectious Diseases Society of America (IDSA), International Society of Anti-Infective Pharmacology (ISAP), Society for Critical Care Medicine (SCCM), and Society of Infectious diseases Pharmacists (SIDP).
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Adapting clinical guidelines to take account of multimorbidity
TL;DR: Care of patients with multimorbidity could be improved if new technology is used to bring together guidelines on individual conditions and tailor advice to each patient’s circumstances, say Bruce Guthrie and colleagues.
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Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials.
Gustavo C Machado,Christopher G. Maher,Paulo H. Ferreira,Marina B. Pinheiro,Chung-Wei Christine Lin,Richard O. Day,Andrew J. McLachlan,Andrew J. McLachlan,Manuela L. Ferreira,Manuela L. Ferreira +9 more
TL;DR: P acetamol is ineffective in the treatment of low back pain and provides minimal short term benefit for people with osteoarthritis, and these results support the reconsideration of recommendations to use paracetamol for patients with low backPain and osteOarthritis of the hip or knee in clinical practice guidelines.
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Ethnic differences in the relationship between insulin sensitivity and insulin response: A systematic review and meta-analysis
Keiichi Kodama,Damon Tojjar,Satoru Yamada,Kyoko Toda,Chirag J. Patel,Chirag J. Patel,Atul J. Butte,Atul J. Butte +7 more
TL;DR: The genetic background of Africans and East Asians makes them more and differentially susceptible to diabetes than Caucasians, and this ethnic stratification could be implicated in the different natural courses of diabetes onset.
References
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David Atkins,Martin P Eccles,Signe Flottorp,Gordon H. Guyatt,David Henry,Suzanne Hill,Alessandro Liberati,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Holger J. Schünemann,Tessa Tan-Torres Edejer,Gunn Elisabeth Vist,John W Williams +14 more
TL;DR: The objective was to critically appraise six prominent systems for grading levels of evidence and the strength of recommendations as a basis for agreeing on characteristics of a common, sensible approach.