GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
Reads0
Chats0
TLDR
The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.Abstract:
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwideread more
Citations
More filters
Journal ArticleDOI
Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis.
TL;DR: Peppermint oil was found to be significantly superior to placebo for global improvement of IBS symptoms and improvement in abdominal pain and its efficacy relative to other IBS treatments including antidepressants and antispasmodic drugs.
Journal ArticleDOI
CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022
TL;DR: In this paper , the authors provide recommendations for clinicians providing pain care, including those prescribing opioids, for outpatients aged ≥18 years, for chronic pain management, including managing acute, subacute and chronic pain.
Journal ArticleDOI
2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis
Sharon A. Chung,Carol A. Langford,Mehrdad Maz,Andy Abril,Mark Gorelik,Gordon H. Guyatt,Amy M. Archer,Doyt L. Conn,Kathy A. Full,Peter C. Grayson,Maria Ibarra,Lisa Imundo,Susan Kim,Peter A. Merkel,Rennie L. Rhee,Philip Seo,John H. Stone,Sangeeta Sule,Robert P. Sundel,Omar I. Vitobaldi,Ann Warner,Kevin Byram,Anisha B. Dua,Nedaa Husainat,Karen E. James,Mohamad A. Kalot,Yih Chang Lin,Jason M. Springer,Marat Turgunbaev,Alexandra Villa-Forte,Amy S. Turner,Reem A. Mustafa +31 more
TL;DR: In this article, the authors provided evidence-based recommendations and expert guidance for the management of antineutrophil cytoplasmic antibody-associated vasculitis (AAV), including granulomatosis with polyangiitis (GPA), microscopic polyangisitis (MPA), and eosinophilic granulomas with polyanagliitis (EGPA), which required ≥70% consensus among the Voting Panel.
Journal ArticleDOI
The Developmental Model of Sport Participation: 15 Years After Its First Conceptualization
Jean Côté,Matthew Vierimaa +1 more
TL;DR: The Developmental Model of Sport Participation (DMSP) as discussed by the authors is a model of athlete development which has been comprehensively researched and refined over the last 15-years, and it describes the processes, pathways, and outcomes associated with sport development throughout childhood and adolescence.
Journal ArticleDOI
The identification and management of interstitial lung disease in systemic sclerosis: evidence-based European consensus statements
Anna-Maria Hoffmann-Vold,Toby M. Maher,Edward E Philpot,Ali Ashrafzadeh,Rafic Barake,Simone Barsotti,Cosimo Bruni,Paolo Carducci,Patricia Carreira,Ivan Castellví,Francesco Del Galdo,Jörg H W Distler,Ivan Foeldvari,Paolo Fraticelli,Peter M. George,Bridget Griffiths,Alfredo Guillén-Del-Castillo,Abdul Monem Hamid,Rudolf Horváth,Michael Hughes,Michael Kreuter,Florentine Moazedi-Fuerst,Jacek Olas,Suman Paul,Cinzia Rotondo,Manuel Rubio-Rivas,Andrei Seferian,Andrei Seferian,Michal Tomcik,Yurdagul Uzunhan,Ulrich A. Walker,Ewa Więsik-Szewczyk,Oliver Distler +32 more
TL;DR: The first evidence-based consensus statements were established on guidance for the identification and medical management of systemic sclerosis-associated ILD through a robust modified Delphi process developed by a diverse panel of experts.
References
More filters
Journal ArticleDOI
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
Jacques E. Rossouw,Garnet L. Anderson,Ross L. Prentice,Andrea Z. LaCroix,Charles Kooperberg,Marcia L. Stefanick,Rebecca D. Jackson,Shirley A.A. Beresford,Barbara V. Howard,Karen C. Johnson,Jane Morley Kotchen,Judith K. Ockene +11 more
TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
Journal ArticleDOI
Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women
Stephen B. Hulley,Deborah Grady,Trudy L. Bush,Curt D Furberg,David M. Herrington,Betty Riggs,Eric Vittinghoff +6 more
TL;DR: Treatment with oral conjugated equine estrogen plus medroxyprogesterone acetate did not reduce the overall rate of CHD events in postmenopausal women with established coronary disease and the treatment did increase the rate of thromboembolic events and gallbladder disease.
Journal ArticleDOI
Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.
Echt Ds,Philip R. Liebson,Mitchell Lb,Robert W. Peters,Obias-Manno D,Barker Ah,Arensberg D,Baker A,Lawrence S. Friedman,Greene Hl +9 more
TL;DR: There was an excess of deathsDue to arrhythmia and deaths due to shock after acute recurrent myocardial infarction in patients treated with encainide or flecainide.
Journal ArticleDOI
A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction.
TL;DR: Finding and analyzing all therapeutic trials in a given field has become such a difficult and specialized task that the clinical experts called on to summarize the evidence in a timely fashion need access to better databases and new statistical techniques to assist them.
Journal ArticleDOI
Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group.
David Atkins,Martin P Eccles,Signe Flottorp,Gordon H. Guyatt,David Henry,Suzanne Hill,Alessandro Liberati,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Holger J. Schünemann,Tessa Tan-Torres Edejer,Gunn Elisabeth Vist,John W Williams +14 more
TL;DR: The objective was to critically appraise six prominent systems for grading levels of evidence and the strength of recommendations as a basis for agreeing on characteristics of a common, sensible approach.